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N/A N=91 Randomized Treatment

Intensive Insulin Treatment and Ischemic Foot Ulcer

Ischemic Foot Ulcer

Enrolled (actual)
91
Serious AEs
0.0%
Results posted
Dec 2015
Primary outcome: Primary: Ischemic Foot Ulcer — 3; 10 participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Intensified insulin treatment (Drug); Standard treatment (Drug)
Age
Adult · 18+ yrs
Sex
All
Sponsor
Karolinska Institutet
Primary completion
Dec 2011

Outcome Measures

OutcomeResultp-value
PRIMARY
Ischemic Foot Ulcer
3; 10

Summary

We aim to investigate the relationship between skin microvascular function and the first hospitalization for ischemic foot ulcer in patients with type 1 diabetes former randomized during 7.5 years to intensified conventional insulin treatment (ICT) compared to standard insulin treatment (ST).

Eligibility Criteria

Inclusion Criteria

Born 1930 or later, Type 1 diabetes appearing at age 30 or earlier and with insulin dependency within 1 year from diagnosis, no known abuse of alcohol or drugs, non-prolipherative retinopathy of any degree present, no previous photocoagulation, normal serum creatinine, unsatsifactory blood glucose control according to the physician in charge of the patients.

Exclusion Criteria

Any history or ongoing ischemic foot ulcer,or peripheral artery disease,or osteoartropathy.

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT01957930). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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