N/A
N=100
Use of Saline-Washed Platelet and Red Cell Transfusions in Adult Acute Leukemia
Leukemia, Myeloid, Acute · Leukemia, Lymphoblastic, Acute
Bottom Line
View on ClinicalTrials.gov: NCT01976442 ↗Enrolled (actual)
100
Serious AEs
—
Results posted
Apr 2017
Primary outcome: Primary: Survial Rate at 30 Days — 100; 97 percentage of participants
Study Design & Population
- Study type
- Observational
- Phase
- N/A
- Interventions
- —
- Age
- Pediatric, Adult
- Sex
- All
- Sponsor
- University of Rochester
- Primary completion
- Nov 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Survial Rate at 30 Days |
100; 97 | — |
| PRIMARY Survial Rate at 60 Days |
97; 94 | — |
| PRIMARY Survial Rate at 100 Days |
96; 87 | — |
| PRIMARY Survial Rate at 5 Years |
55; 39 | — |
Summary
The purpose of this study is to determine whether a novel standard of care protocol, washing red cell and platelet transfusions for younger patients with acute leukemia, has yielded improved clinical outcomes at Strong Memorial Hospital (Rochester, New York, USA). This standard of care was implemented based upon an earlier randomized trial (BMC Blood Disorders. 2004 Dec 10;4(1):6) The comparator will be historical controls from the medical literature.
Eligibility Criteria
Inclusion Criteria
- previously untreated patients with a diagnosis of acute leukemia between the ages of 0 and 50 (AML) and 18 and 50 (ALL)
Exclusion Criteria
- all other patients
Data sourced from ClinicalTrials.gov (NCT01976442). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.