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N/A N=16,231 Randomized Single-blind Screening

Randomized Trial of In-Home Cervical Cancer Screening in Underscreened Women

Cervical Cancer

Enrolled (actual)
16,231
Serious AEs
0.0%
Results posted
Sep 2020
Primary outcome: Primary: Number of Participants Diagnosed With Cervical Epithelial Neoplasia Grade 2 or Worse — 12; 8 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Mailed in-home high-risk HPV testing kit (Behavioral); Usual care (Other)
Age
Adult · 30+ yrs
Sex
Female
Sponsor
University of Washington
Primary completion
Feb 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants Diagnosed With Cervical Epithelial Neoplasia Grade 2 or Worse
12; 8
PRIMARY
Number of Participants That Received Treatment for Cervical Intraepithelial Neoplasia Grade 2 or Worse
12; 7
SECONDARY
Number of Participants That Completed Uptake of Cervical Cancer Screening
2618; 1719
SECONDARY
Number of Participants With an Abnormal Screening Result
225; 114
SECONDARY
Experiences and Attitudes Associated With In-home HPV Testing Uptake
116; 156; 119; 964
SECONDARY
Experiences and Attitudes Associated With Follow-up of Positive In-home HPV Testing Results
46; 29

Summary

The purpose of this trial is to determine whether mailing in-home human papillomavirus (HPV) screening kits is effective in increasing uptake of cervical cancer screening and early detection and treatment of cervical neoplasia in underscreened women.

Eligibility Criteria

Inclusion Criteria

  • Female
  • 30 to 64 years of age
  • Have a primary care provider at Group Health
  • Received annual "birthday letter" with Pap screening reminder 5 months earlier
  • No Pap test in the past 3.4 years
  • Continuously enrolled at Group Health for at least 3.4 years
  • No hysterectomy

Exclusion Criteria

  • Currently pregnant
  • Language interpreter needed
  • On "do not contact list" for research studies
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02005510). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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