N/A
N=9
Effect of Sucrose on Liver Fat
Healthy Volunteers
Bottom Line
View on ClinicalTrials.gov: NCT02015442 ↗Enrolled (actual)
9
Serious AEs
0.0%
Results posted
Nov 2019
Primary outcome: Primary: Percentage Change in Liver Fat — 1.9; 1.9 percentage of change — p=0.390
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Sucrose (Dietary_supplement)
- Age
- Adult · 20+ yrs
- Sex
- Male
- Sponsor
- Imperial College London
- Primary completion
- Oct 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Percentage Change in Liver Fat |
1.9; 1.9 | 0.390 |
| SECONDARY Changes in Fasting Triglyceride Levels |
0.9; 0.9; 0.8; 0.7 | 0.001 sig |
Summary
AIMS To determine the effect of high and low sucrose diets on liver fat in healthy adult men with liver fat levels below 5%
Eligibility Criteria
Inclusion Criteria
Healthy men aged between 20 and 40 years with BMI between 20-25 kg/m2 and with normal liver fat levels ( 2 units per day)
- Exceeding UK minimum activity recommendation (30min moderate exercise 5d/wk)
- Current smokers (smoked within last 6 months)
- Any gastrointestinal disorder e.g. Crohn's disease, coeliac disease or irritable bowel syndrome
- A history of drug or alcohol abuse in the last 2 years
- Pancreatitis
- Unable to have MRI (eg. metallic or magnetic implants, claustrophobia)
Data sourced from ClinicalTrials.gov (NCT02015442). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.