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N/A N=124

Newborn Feeding and Infant Phenotype

Breast Feeding

Enrolled (actual)
124
Serious AEs
0.0%
Results posted
Jun 2019
Primary outcome: Primary: Change in Total Adipose Tissue Volume — 0.718; 0.901; 0.775 Litres

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Age
Pediatric
Sex
All
Sponsor
Imperial College London
Primary completion
Jul 2012

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Total Adipose Tissue Volume
0.718; 0.901; 0.775
SECONDARY
Change in Regional Adipose Tissue Distribution Compared to Breastfed Infants.
-0.07; -0.06; -0.03
SECONDARY
Change in Intrahepatocellular Lipid Compared to Breastfed Infants.
1.192; -0.054; 1.095

Summary

Breast feeding is believed to be beneficial to long-term health but how these effects are mediated is unknown. I suggest that this may be through effects on body composition and metabolism. I will compare adipose tissue and liver fat deposition in healthy, full term breast and formula fed infants babies shortly after birth and around 12 weeks.

Eligibility Criteria

Inclusion Criteria

  • Healthy baby
  • Term baby
  • Appropriate weight for gestational age (UK - WHO 2009 growth charts)

Exclusion Criteria

  • Infants of diabetic mothers
  • Infants of smokers
  • Infants fed non-commercial or non-cows milk based infant formulae
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02033005). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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