N/A
Completed N=5
CPB Versus Sham Treatment for Pain Management in Small Duct Chronic Pancreatitis
Source: ClinicalTrials.gov NCT02054910 ↗Enrolled (actual)
5
Serious AEs
0.0%
Results posted
Feb 2017
Primary outcomePrimary: Change in Pain Response Over a 6 Month Period of Time Using the VAS Score
Summary
This study assesses the pain response to Endoscopic Ultrasound (EUS) guided Celiac Plexus Block (CPB) treatment in comparison to EUS without a pain block administered. All participants will receive medications for pain as needed.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Pain Response Over a 6 Month Period of Time Using the VAS Score |
— | — |
| SECONDARY Mean Quality of Life Score Between Each Group at 6 Months |
— | — |
| SECONDARY Number of Subject in Each Group Requiring Administration of Narcotics During 6 Months Post Baseline |
— | — |
| SECONDARY Mean Mental State Between Groups Using the Beck's Depression Index at 6 Months. |
— | — |
| SECONDARY Mean Number of Times Subjects in Each Group Accessed the Health Care System Within 6 Months Post Procedure |
— | — |
| SECONDARY % of Subjects in Each Group That Are Employed at 6 Months Post Procedure. |
— | — |
Eligibility Criteria
Inclusion Criteria
- All patients referred to UAB Endoscopy Unit for with known chronic pancreatitis
- Patients referred to the endoscopy unit with abdominal pain with suspicion of chronic pancreatitis meeting 5 of 9 parenchymal and ductal changes (i.e. lobulations, hyperechoic stranding, hyperechoic foci, cysts, calcification, irregular duct, hyperechoic walls, side branch dilations and ductal calculi).
Exclusion Criteria
- Age 1.6, Prothrombin Time >18secs, Thrombocytopenia <80,000 cells/ml)
- Unable to consent
- Non-English speaking patients.
- Previously undergone CPB
- Pregnancy and Breast feeding
- Patients with ductal strictures, calcification, pancreatic ductal calculi, pseudocysts.
- Previous pancreatic surgery
- Previous pseudocyst drainage
- Other documented causes of abdominal pain.
Data sourced from ClinicalTrials.gov (NCT02054910). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.