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Phase 4 N=44 Randomized Triple-blind Treatment

Conditioned Pharmacotherapeutic Effects in Hypertension

Hypertension

Enrolled (actual)
44
Serious AEs
0.0%
Results posted
Jun 2019
Primary outcome: Primary: Mean Systolic Blood Pressure — 151.59; 152.64; 155.42; 151.74 mmHg

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
carvedilol (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Rochester
Primary completion
Nov 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Systolic Blood Pressure
138.90; 136.38; 139.27; 134.94
PRIMARY
Mean Systolic Blood Pressure
138.90; 136.38; 139.27; 134.94
PRIMARY
Mean Systolic Blood Pressure
138.90; 136.38; 139.27; 134.94

Summary

The proposed research is designed to determine if the application of classical conditioning operations could influence the clinical effects of a regimen of antihypertensive drug therapy. It will be determined if, capitalizing on conditioned pharmacotherapeutic effects, patients can be effectively treated with smaller cumulative amounts of drug.

Eligibility Criteria

Inclusion Criteria

  • systolic blood pressure between 140-160 mmHG
  • between 18-80 years old

Exclusion Criteria

  • abnormal renal function
  • currently pregnant, or trying to become pregnant
  • being treated with a beta-blocker
  • use of illicit drugs
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02056626). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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