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N/A N=62 Other

Clinical Evaluation of an Integrated PET/MRI System

Subjects With Clinical Indication for PET/CT

Enrolled (actual)
62
Serious AEs
0.0%
Results posted
Apr 2019
Primary outcome: Primary: Number Usable PET/MRI Image Sets — 70 Usable image sets

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
PET/MRI system (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
GE Healthcare
Primary completion
Aug 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Number Usable PET/MRI Image Sets
70
PRIMARY
Number of Diagnostic Quality Images
67

Summary

The investigational PET/MRI scanner, including attenuation correction method, is capable of producing diagnostic quality images and appropriate device functionality per user feedback.

Eligibility Criteria

Inclusion Criteria

  • Subject must have a clinical indication for a PET/CT exam
  • Subject must be at least eighteen (18) years of age; and
  • Female subjects that are determined to be non-pregnant by a physician investigator or are demonstrated non-pregnant by negative urine pregnancy test administered within the 24 hour period before PET/CT imaging; and
  • Subject must be able to hear and understand instructions without assistive devices; and
  • Subject must provide written informed consent; and
  • Subject has the necessary mental capacity to understand instructions, and is able to comply with protocol requirements; and
  • Subject is able to remain still for duration of imaging procedure (approximately 60 minutes total for PET/MRI); and
  • Subject must be able to participate in a PET/MR imaging session within 2 hours of concluding their PET/CT exam and within 4 hours of PET radiotracer administration.

Exclusion Criteria

  • Subjects who have any axial diameter larger than 55 cm; or
  • Subjects with a weight greater than 227 kgs; or
  • Subjects that have metallic/conductive or electrically/magnetically active implants without MR Safe or MR Conditional labeling, with the exception of dental devices/fillings, surgical clips, and surgical staples determined to be safe for MRI scanning by a physician investigator; or
  • Subjects that have implants with MR Unsafe labeling; or
  • Subjects that have implants labeled as MR Conditional by the manufacturer for which the allowable conditions are not expected to be achieved by the MR/PET environment or scan protocol ; or
  • Subjects who have a contraindication to MRI according to the screening policy of the participating site
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02071706). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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