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N/A N=15 Randomized Single-blind

DAILIES TOTAL1® Lubricity Post Wear

Refractive Error

Enrolled (actual)
15
Serious AEs
0.0%
Results posted
May 2015
Primary outcome: Primary: Average Coefficient of Friction (CF) at 16 Hours Compared to Unworn — 0.0394; 0.0396 unitless

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Delefilcon A contact lenses (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Alcon Research
Primary completion
Apr 2014

Outcome Measures

OutcomeResultp-value
PRIMARY
Average Coefficient of Friction (CF) at 16 Hours Compared to Unworn
0.0394; 0.0396
SECONDARY
Average Coefficient of Friction at 15 Minutes
0.0392

Summary

The primary objective of the study is to demonstrate that the lubricity of DAILIES TOTAL1® (DT1) lenses after 16 hours of wear is equivalent to the lubricity of unworn DT1 lenses.

Eligibility Criteria

Inclusion Criteria

  • Willing and able to sign Informed Consent document.
  • Adapted, current soft contact lens wearer.
  • Requires contact lens powers within the specified range of -0.50 diopters (D) to -10.00D.
  • Cylinder between 0.00D and -1.00D (inclusive) in both eyes at Visit 1 manifest refraction.
  • Vision correctable to 20/25 or better in each eye at distance with study lenses.
  • Willing to wear study lenses at least 16 waking hours in one day and attend all study visits.
  • Able to be successfully fitted with study lenses.
  • Other protocol-specified inclusion criteria may apply.

Exclusion Criteria

  • Any ocular infection, inflammation, abnormality or active disease that would contraindicate contact lens wear, as determined by the Investigator.
  • Use of systemic or ocular medications for which contact lens wear could be contraindicated, as determined by the Investigator.
  • Use of artificial tears and rewetting drops during the study.
  • Monocular (only one eye with functional vision) or fit with only one lens.
  • Any abnormal ocular condition observed during the Visit 1 slit lamp examination.
  • History of herpetic keratitis, ocular surgery, or irregular cornea.
  • Pregnant.
  • Participation in any clinical study within 30 days of Visit 1.
  • Other protocol-specified exclusion criteria may apply.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02072980). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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