N/A
N=140
Nitrous Oxide for Pain Management of First Trimester Surgical Abortion
Abortion in First Trimester
Bottom Line
View on ClinicalTrials.gov: NCT02096575 ↗Enrolled (actual)
140
Serious AEs
0.0%
Results posted
Mar 2016
Primary outcome: Primary: Visual Analog Pain Score for Mean Maximum Procedural Pain — 54.37; 60.48 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Nitrous oxide administration (Other)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Female
- Sponsor
- University of New Mexico
- Primary completion
- Apr 2015
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Visual Analog Pain Score for Mean Maximum Procedural Pain |
54.37; 60.48 | — |
| SECONDARY Visual Analog Scale Score for Baseline Pain |
4.7426; 4.4388 | — |
| SECONDARY Visual Analog Scale for Post-procedure Pain |
26.68; 25.96 | — |
| SECONDARY Pain Management Satisfaction |
69.3382; 61.5373 | — |
| SECONDARY Visual Analog Scale to Measure Anticipated Pain. |
56.1544; 50.3104 | — |
Summary
The purpose of this research is to study the effect of nitrous oxide on pain felt by women having a surgical termination at less than 11 weeks compared to pain felt by women receiving oral pain medications.
Eligibility Criteria
Inclusion Criteria
- 18 years old or older,
- elective pregnancy termination at gestational age of less than 11 weeks,
- speak English
- candidate for an in-clinic procedure.
- desire local anesthesia, ibuprofen, Vicodin and Ativan (the usual treatment in our clinic) for managing pain
Exclusion Criteria
- no medical problems preventing the use of nitrous oxide
- no allergies to nitrous oxide, lidocaine, vasopressin, ibuprofen, Vicodin or Ativan
- significant active upper respiratory infection
- chronic obstructive pulmonary disease (COPD)
- intoxication
- use of street drugs
Data sourced from ClinicalTrials.gov (NCT02096575). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.