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Phase 4 Completed N=40 Randomized Triple-blind Treatment

Ultrasound-guided Adductor Canal Block for Total Knee Replacement

Complications; Arthroplasty · Knee Injuries
Source: ClinicalTrials.gov NCT02100579 ↗
Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Nov 2016
Primary outcomePrimary: Opioid Consumption (mg morEq) — 48; 60 Morphine Equivalents
◆ Published Evidence
No publication linked

No peer-reviewed publication reporting this trial's results has been linked yet. This can indicate results are unpublished — a known publication-bias signal. We re-check periodically.

Summary

Total knee arthroplasty is associated with intense early postoperative pain. Fast track recovery programs including early therapy protocols and early hospital discharge are being implemented at various hospitals. The postoperative analgesic pain regimen should enhance functional recovery in addition to providing efficient analgesia with minimal side effects. Adductor canal blockade is commonly used to provide postoperative analgesia for total knee arthroplasty (TKA) surgery. The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.

Outcome Measures

OutcomeResultp-value
PRIMARY
Opioid Consumption (mg morEq)
48; 60
SECONDARY
Visual Analog Scale Pain Score
71; 131
SECONDARY
Length of Hospitalization
73; 92

Eligibility Criteria

Inclusion Criteria

  • Participants 40 to 75 years old who are presenting for minimally invasive total knee arthroplasty under spinal anesthesia

Exclusion Criteria

  • Patient refusal
  • American Society of Anesthesiologists physical status classification of 4 or higher
  • Pre-existing neuropathy in the femoral or sciatic distribution
  • Coagulopathy
  • Infection at the site
  • Chronic opioid use (greater than 3 months)
  • Pregnancy
  • Medical conditions limiting physical therapy participation
  • Any other contra-indication to regional anesthesia
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02100579). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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