Phase 4
N=40
Ultrasound-guided Adductor Canal Block for Total Knee Replacement
Complications; Arthroplasty · Knee Injuries
Bottom Line
View on ClinicalTrials.gov: NCT02100579 ↗Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Nov 2016
Primary outcome: Primary: Opioid Consumption (mg morEq) — 48; 60 Morphine Equivalents
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 4
- Interventions
- Bupivacaine (Drug); Preservative free normal saline (Drug)
- Age
- Adult, Older Adult · 40+ yrs
- Sex
- All
- Sponsor
- Northwestern University
- Primary completion
- Oct 2015
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Opioid Consumption (mg morEq) |
48; 60 | — |
| SECONDARY Visual Analog Scale Pain Score |
71; 131 | — |
| SECONDARY Length of Hospitalization |
73; 92 | — |
Summary
Total knee arthroplasty is associated with intense early postoperative pain. Fast track recovery programs including early therapy protocols and early hospital discharge are being implemented at various hospitals. The postoperative analgesic pain regimen should enhance functional recovery in addition to providing efficient analgesia with minimal side effects. Adductor canal blockade is commonly used to provide postoperative analgesia for total knee arthroplasty (TKA) surgery. The investigators hypothesize that an ultrasound guided adductor canal block will lower narcotic consumption and improved overall satisfaction compared to ultrasound guided sham block with normal saline (placebo) for patients undergoing minimally invasive TKA surgery.
Eligibility Criteria
Inclusion Criteria
- Participants 40 to 75 years old who are presenting for minimally invasive total knee arthroplasty under spinal anesthesia
Exclusion Criteria
- Patient refusal
- American Society of Anesthesiologists physical status classification of 4 or higher
- Pre-existing neuropathy in the femoral or sciatic distribution
- Coagulopathy
- Infection at the site
- Chronic opioid use (greater than 3 months)
- Pregnancy
- Medical conditions limiting physical therapy participation
- Any other contra-indication to regional anesthesia
Data sourced from ClinicalTrials.gov (NCT02100579). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.