N/A
N=165
Epidural Catheter With or Without Adductor Canal Nerve Block for Postoperative Analgesia Following Total Knee Arthroplasty
Arthroplasty, Replacement, Knee · Nerve Block
Bottom Line
View on ClinicalTrials.gov: NCT02121392 ↗Enrolled (actual)
165
Serious AEs
0.0%
Results posted
Oct 2020
Primary outcome: Primary: Morphine Equivalents — 11.9; 12.5; 96.5; 73.9 milligrams of morphine
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Adductor Canal Nerve Block Catheter (Device); Adductor Canal Nerve Block Sham Catheter (Device); Bupivacaine (Drug)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- University of Chicago
- Primary completion
- Jan 2017
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Morphine Equivalents |
11.9; 12.5; 96.5; 73.9 | — |
| SECONDARY Visual Analog Score for Pain |
27.9; 26.9; 36.4; 28.6 | — |
| SECONDARY Physical Therapy Ambulation Distance |
13.8; 17.6; 32.5; 39.4 | — |
| SECONDARY Number of Hospital Days Until Discharge Criteria Are Met |
2.42; 2.67 | — |
| SECONDARY Number of Participants With Bleeding Complications at Adductor Canal Nerve Block Catheter Site |
0; 0 | — |
| SECONDARY Number of Participants With Adverse Events Related to Adductor Canal Nerve Block Catheter |
0; 0 | — |
| SECONDARY Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) |
37.8; 29.1; 32.9; 27.9 | — |
| SECONDARY Range of Motion |
51.4; 40.6; 71.3; 62.5 | — |
| SECONDARY Range of Motion at 3 and 6 Week Follow up |
98.2; 94.3; 109; 105 | — |
Summary
The purpose of this study is to further investigate the efficacy of adductor canal nerve blocks for pain management after total knee replacement. Specifically we are studying adductor canal nerve blocks in conjunction with epidural anesthesia, which is a combination that has not been extensively researched before. Our question is whether combining these modalities will enhance patient satisfaction after surgery and accelerate patients' readiness to discharge.
Eligibility Criteria
Inclusion Criteria
- end stage degenerative joint disease
- enrolled for unilateral total knee arthroplasty at the University of Chicago
- age 85
- American Society of Anesthesiologists physical status > 3
- known hypersensitivity to lidocaine, bupivacaine, ropivacaine or other local anesthetic agents
- Coagulopathy, specifically INR > 1.5, Platelets 50 mg morphine equivalent daily of opioids
- Pre-existing femoral neuropathy or radiculopathy
- Patients with poor ability to communicate
Data sourced from ClinicalTrials.gov (NCT02121392). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.