N/A
Completed N=274
Extending Long-term Outcomes Through an Adaptive Aftercare Intervention
Cocaine Use Disorder · Contingency Management
Source: ClinicalTrials.gov NCT02143063 ↗
Enrolled (actual)
274
Serious AEs
69.0%
Results posted
Nov 2021
Primary outcomePrimary: Longest Duration of Abstinence From Cocaine — 4.14; 6.64; 6.93 weeks — p=.01
Summary
Reinforcement interventions have pronounced effects on reducing cocaine use. This study will evaluate a novel approach in which reinforcement frequency varies by patient performance. To test efficacy, 280 patients with cocaine use disorder will be randomly assigned to: standard care, standard care plus traditional twice weekly reinforcement, or standard care plus adaptive variable interval reinforcement.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Longest Duration of Abstinence From Cocaine |
4.14; 6.64; 6.93 | .01 sig |
| SECONDARY Longest Duration of Abstinence From All Substances Tested |
4.75; 5.93; 5.71 | .02 sig |
Eligibility Criteria
Inclusion Criteria
- be age 18 years or older
- have a cocaine use disorder diagnosis
- be willing to sign informed consent and able to pass an informed consent quiz
Exclusion Criteria
- serious, uncontrolled psychiatric illness
- in recovery from pathological gambling
- do not speak English
Data sourced from ClinicalTrials.gov (NCT02143063). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.