N/A N=14 Prevention

Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia

Blood Volume Analysis

Bottom Line

View on ClinicalTrials.gov: NCT02148809 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jun 2017

Primary outcome: Primary: Change in Total Blood Volume — 487 ml

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: 1mL of I-131 Human Serum Albumin is injected prior to the measurements (Radiation)
Age: Adult, Older Adult · 50+ yrs
Sex: All
Sponsor: Hospital for Special Surgery, New York
Primary completion: Nov 2015

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Total Blood Volume	487	—

Summary

Hypotensive Anesthesia is a type of regional anesthesia performed routinely at our hospital. This type of anesthesia reduces the average arterial pressure. Benefits include reduced bleeding and lower risk of blood clots. The purpose of this study is to determine the effect of intravenous fluids administered with hypotensive anesthesia on your blood volume. With this parameter we will be able to understand how much of your blood is lost because of bleeding and how much of the drop is related to dilution. Study hypothesis: Hemodilution associated with intravenous fluid substitution during hypotensive anesthesia results in decreased postoperative hemoglobin (Hb) levels

Eligibility Criteria

Inclusion Criteria

Non- inflammatory degenerative joint disease of the hip
Patients scheduled for unilateral primary total hip arthroplasty
Age between 50 and 75 years
Hypotensive Spinal-epidural anesthesia with systolic BP 1.5)
Aortic or mitral valve disease
Pulmonary hypertension
Revision Hip Surgery
Inadequate intravenous fluid substitution within the first 6 hrs (<3 liters)
Inadequate hypotensive anesthesia (mean arterial pressure above 65 for more than 33% of the surgical time

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02148809). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.