N/A
Completed N=14
Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia
Blood Volume Analysis
Source: ClinicalTrials.gov NCT02148809 ↗
Enrolled (actual)
14
Serious AEs
0.0%
Results posted
Jun 2017
Primary outcomePrimary: Change in Total Blood Volume — 487 ml
Summary
Hypotensive Anesthesia is a type of regional anesthesia performed routinely at our hospital. This type of anesthesia reduces the average arterial pressure. Benefits include reduced bleeding and lower risk of blood clots.
The purpose of this study is to determine the effect of intravenous fluids administered with hypotensive anesthesia on your blood volume. With this parameter we will be able to understand how much of your blood is lost because of bleeding and how much of the drop is related to dilution.
Study hypothesis: Hemodilution associated with intravenous fluid substitution during hypotensive anesthesia results in decreased postoperative hemoglobin (Hb) levels
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Total Blood Volume |
487 | — |
Eligibility Criteria
Inclusion Criteria
- Non- inflammatory degenerative joint disease of the hip
- Patients scheduled for unilateral primary total hip arthroplasty
- Age between 50 and 75 years
- Hypotensive Spinal-epidural anesthesia with systolic BP 1.5)
- Aortic or mitral valve disease
- Pulmonary hypertension
- Revision Hip Surgery
- Inadequate intravenous fluid substitution within the first 6 hrs (<3 liters)
- Inadequate hypotensive anesthesia (mean arterial pressure above 65 for more than 33% of the surgical time
Data sourced from ClinicalTrials.gov (NCT02148809). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.