N/A N=97

A Comparison of Ropivacaine Alone Versus Combination of Dexamethasone and Clonidine for Block

Upper Extremity Surgery

Bottom Line

View on ClinicalTrials.gov: NCT02151487 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2019

Primary outcome: Primary: Duration of the Sensorial Supraclavicular Block — 13.4; 14; 17.4; 18.8 hour

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: Ropivacaine (Drug); Ropivacaine and dexamethasone (Drug); Ropivacaine and clonidine (Drug); Ropivacaine, dexamethasone and clonidine (Drug)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Texas Southwestern Medical Center
Primary completion: Apr 2016

Outcome Measures

Outcome	Result	p-value
PRIMARY Duration of the Sensorial Supraclavicular Block	13.4; 14; 17.4; 18.8	—
SECONDARY Postoperative Analgesia	0; 0; 0; 0	—

Summary

The aim of this randomized, observer-blinded study is to evaluate the postoperative analgesic efficacy of adding dexamethasone and clonidine to ropivacaine in supraclavicular nerve block. The investigators hypothesized that addition of dexamethasone and clonidine to ropivacaine would prolong the duration of analgesia in supraclavicular nerve block compared with ropivacaine alone.

Eligibility Criteria

Inclusion Criteria

Men and women 18-80 years old
Undergoing upper extremity surgery
Receiving Supraclavicular block
Receiving ropivacaine, ropivacaine adjuvants (dexamethasone, clonidine) for the supraclavicular nerve block.
Able to give Informed consent

Exclusion Criteria

Age less than 18 and greater than 80 years
Inability to understand the study procedures
Significant respiratory dysfunction
Preexisting neurologic deficits
Allergy to local anesthetics
A bleeding diathesis or on anticoagulants
Systemic glucocorticoid use
Refuse to participate in the study

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02151487). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.