N/A N=40 Randomized Triple-blind Treatment

Effect of Prewarming on Microcirculatory Response

Coronary Artery Bypass Graft Triple Vessel

Bottom Line

View on ClinicalTrials.gov: NCT02186210 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Oct 2018

Primary outcome: Primary: Recovery Slope — 2.8; 3.1 % / sec (recovery slope unit)

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: prewarming (Device)
Age: Adult, Older Adult · 20+ yrs
Sex: All
Sponsor: Seoul National University Hospital
Primary completion: May 2015

Outcome Measures

Outcome	Result	p-value
PRIMARY Recovery Slope	2.8; 3.1	—
SECONDARY Tissue Oxygen Saturation	76; 79	—

Summary

Intraoperative hypothermia may affect tissue microcirculation and can induce myocardial injury, wound infection, and coagulopathy. During off-pump coronary artery bypass surgery without cardiopulmonary bypass or induced hypothermia, maintenance of normothermia is important for clinical outcome. The investigators hypothesized that prewarming during induction of general anesthesia would reduce drop of body temperature and change of peripheral microcirculation.

Eligibility Criteria

Inclusion Criteria

off-pump coronary artery bypass surgery

Exclusion Criteria

refuse to enroll
cannot undergo vascular occlusion test: anatomical abnormality of both arms, severe peripheral vascular disease, presence of A-V fistula
preoperative left ventricular ejection fraction < 35%
preoperative continuous infusion of vasopressor or inotropes
pregnancy

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Data sourced from ClinicalTrials.gov (NCT02186210). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.