N/A
Completed N=40
Effect of Prewarming on Microcirculatory Response
Coronary Artery Bypass Graft Triple Vessel
Source: ClinicalTrials.gov NCT02186210 ↗
Enrolled (actual)
40
Serious AEs
0.0%
Results posted
Oct 2018
Primary outcomePrimary: Recovery Slope — 2.8; 3.1 % / sec (recovery slope unit)
Summary
Intraoperative hypothermia may affect tissue microcirculation and can induce myocardial injury, wound infection, and coagulopathy. During off-pump coronary artery bypass surgery without cardiopulmonary bypass or induced hypothermia, maintenance of normothermia is important for clinical outcome. The investigators hypothesized that prewarming during induction of general anesthesia would reduce drop of body temperature and change of peripheral microcirculation.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Recovery Slope |
2.8; 3.1 | — |
| SECONDARY Tissue Oxygen Saturation |
76; 79 | — |
Eligibility Criteria
Inclusion Criteria
- off-pump coronary artery bypass surgery
Exclusion Criteria
- refuse to enroll
- cannot undergo vascular occlusion test: anatomical abnormality of both arms, severe peripheral vascular disease, presence of A-V fistula
- preoperative left ventricular ejection fraction < 35%
- preoperative continuous infusion of vasopressor or inotropes
- pregnancy
Data sourced from ClinicalTrials.gov (NCT02186210). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.