N/A
N=349
A Trial of Rehabilitation Therapy in Older Acute Heart Failure Patients
Acute Decompensated Heart Failure
Bottom Line
View on ClinicalTrials.gov: NCT02196038 ↗Enrolled (actual)
349
Serious AEs
63.3%
Results posted
Jun 2021
Primary outcome: Primary: Short Physical Performance Battery (SPPB) at Month 3 — 6.9; 8.3 score on a scale — p=<0.0001
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- multi-domain rehabilitation intervention (Behavioral); Attention Control (Behavioral)
- Age
- Adult, Older Adult · 60+ yrs
- Sex
- All
- Sponsor
- Wake Forest University Health Sciences
- Primary completion
- Jun 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Short Physical Performance Battery (SPPB) at Month 3 |
6.9; 8.3 | <0.0001 sig |
| SECONDARY All-Cause Rehospitalization |
213; 194 | 0.59 |
Summary
REHAB-HF: A Trial of Rehabilitation Therapy in Older Acute Heart Failure Patients, is a multicenter, randomized, attention-controlled, single-blind trial designed to examine the hypothesis that, in addition to standard care, a novel, tailored, progressive, multi-domain rehabilitation intervention administered to older patients with acute decompensated heart failure (ADHF) beginning early during hospitalization and continuing for 12 weeks will improve physical function and key clinical outcomes, including the rate of rehospitalization.
Eligibility Criteria
Inclusion Criteria
- Age ≥ 60 years old
- In the hospital setting >24 hours for the management of ADHF, or diagnosed with ADHF after being hospitalized for another reason. ADHF will be confirmed by the study physician, and will be defined according to the Food and Drug Administration definition of hospitalized heart failure as a combination of symptoms, signs, and HF-specific medical treatments.
Exclusion Criteria
- Acute myocardial infarction
- Planned discharge other than to home or a facility where the participant will live independently
- Already actively participating in formal, facility-based cardiac rehabilitation
Data sourced from ClinicalTrials.gov (NCT02196038). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.