Phase 3
Completed N=86
Usefulness of BiClamp Forceps for Liver Resection: A Randomized Clinical Trial
Hepatobiliary Disease
Source: ClinicalTrials.gov NCT02197481 ↗
Enrolled (actual)
86
Serious AEs
7.0%
Results posted
Dec 2017
Primary outcomePrimary: The Total Blood Loss — 376.73; 339.81 ml
◆ Published Evidence
Highly cited
572citations · ~25 / year
Influence of transfusions on perioperative and long-term outcome in patients following hepatic resection for colorectal metastases.
Summary
The purpose of this study is to compare short-term and long-term efficacy of BiClamp forceps hepatectomy and clamp-crushing technique for parenchymal transection during elective hepatic resection.
Linked Publications (4)
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Influence of transfusions on perioperative and long-term outcome in patients following hepatic resection for colorectal metastases.
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Techniques for liver parenchymal transection in liver resection.
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Impact of the VIO system in hepatic resection for patients with hepatocellular carcinoma.
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BiClamp® forcep liver transection versus clamp crushing technique for liver resection: study protocol for a randomized controlled trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Total Blood Loss |
376.73; 339.81 | — |
| SECONDARY Liver Transection Time |
25.51; 26.21 | — |
| SECONDARY Mortality |
0; 0 | — |
| SECONDARY Morbidity |
13; 12 | — |
| SECONDARY Biliary Leakage |
4; 2 | — |
| SECONDARY Duration of Postoperative Hospital Stay |
8.65; 8.81 | — |
| SECONDARY Number of Participants Requiring a Blood Transfusion |
2; 4 | — |
| SECONDARY Total Bilirubin |
17.70; 18.46 | — |
Eligibility Criteria
Inclusion Criteria
- Both male and female, aged 18 or older
- Patients scheduled to undergo hepatic resection for some benign or malignant hepatobiliary disease
- Child-Pugh class A or B liver function
- BiClamp forceps hepatectomy and clamp-crushing feasible based on preoperative imaging
- No tumor invasion the main vein, hepatic artery and vein and major inferior vena cava
- No extrahepatic metastasis
- Voluntary participation in the study, and informed consent.
Exclusion Criteria
- Age 65 years , pregnant or lactating women
- Preoperative liver function evaluation: Child-Pugh C grade
- Laparoscopic hepatectomy
- Extrahepatic metastasis
- Tumor invasion the main vein, hepatic artery and vein and major inferior vena cava
- The patient refused to sign the informed consent form
Data sourced from ClinicalTrials.gov (NCT02197481) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.