N/A
N=932
Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis
Surgical Site Infection
Bottom Line
View on ClinicalTrials.gov: NCT02202577 ↗Enrolled (actual)
932
Serious AEs
0.0%
Results posted
Jul 2022
Primary outcome: Primary: Number of Patients With Surgical Site Infection — 29; 33 Participants — p=0.38
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Chlorhexidine - Isopropyl alcohol (Drug); Povidone-Iodine Scrub and Paint (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Female
- Sponsor
- Case Western Reserve University
- Primary completion
- Jul 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Patients With Surgical Site Infection |
29; 33 | 0.38 |
| SECONDARY Number of Patients With Non-infections Surgical Site Complications |
19; 17 | — |
Summary
Primary Hypothesis: chlorhexidine gluconate alcohol skin antiseptic preparation is superior to povidone-iodine scrub and paint skin antiseptic preparation for prevention of cesarean related surgical site infection.
Eligibility Criteria
Inclusion Criteria
- cesarean delivery
- age 18-65
- ability to consent in English or Spanish
Exclusion Criteria
- inability or unwillingness to consent to study participation in English or Spanish
- current incarceration
- pre-operative diagnosis of chorioamnionitis
- perceived inability to complete follow up for data collection
- any prior known allergy or adverse reaction to either study preparation
Data sourced from ClinicalTrials.gov (NCT02202577). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.