Phase 4 N=30 Other

Effect of Electronic Cigarette Use on Cough Reflex Sensitivity

Cough

Bottom Line

View on ClinicalTrials.gov: NCT02203162 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2016

Primary outcome: Primary: Change in Cough Reflex Sensitivity (Log C5) — -0.29; 0.24 log C5

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: electronic cigarette exposure (Device)
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: Montefiore Medical Center
Primary completion: Dec 2014

Outcome Measures

Outcome	Result	p-value
PRIMARY Change in Cough Reflex Sensitivity (Log C5)	-0.29; 0.24	—

Summary

Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system. The aim of this study is to evaluate the acute effect of one e-cig vaping session (30 puffs 30 seconds apart) on cough reflex sensitivity in healthy adult nonsmokers.

Eligibility Criteria

Inclusion Criteria

healthy adults (age18 years and above)
nonsmokers

Exclusion Criteria

previous smoker
asthma/other respiratory illness
acute viral upper respiratory tract infection (common cold) in previous 4 weeks

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02203162). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.