Phase 4
Completed N=30
Effect of Electronic Cigarette Use on Cough Reflex Sensitivity
Cough
Source: ClinicalTrials.gov NCT02203162 ↗
Enrolled (actual)
30
Serious AEs
0.0%
Results posted
May 2016
Primary outcomePrimary: Change in Cough Reflex Sensitivity (Log C5) — -0.29; 0.24 log C5
◆ Published Evidence
Established
67citations · ~7 / year
Effect of e-Cigarette Use on Cough Reflex Sensitivity.
Summary
Although electronic cigarettes (e-cigs) are now widely used, very little information exists regarding the effect of electronic cigarette use (vaping) on the respiratory system. The aim of this study is to evaluate the acute effect of one e-cig vaping session (30 puffs 30 seconds apart) on cough reflex sensitivity in healthy adult nonsmokers.
Linked Publications
-
Effect of e-Cigarette Use on Cough Reflex Sensitivity.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Cough Reflex Sensitivity (Log C5) |
-0.29; 0.24 | — |
Eligibility Criteria
Inclusion Criteria
- healthy adults (age18 years and above)
- nonsmokers
Exclusion Criteria
- previous smoker
- asthma/other respiratory illness
- acute viral upper respiratory tract infection (common cold) in previous 4 weeks
Data sourced from ClinicalTrials.gov (NCT02203162) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.