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N/A N=131 Randomized Single-blind Treatment

Restylane Perlane to Shape the Nasal Dorsum and/or Nasal Root

Nasal Augmentation

Enrolled (actual)
131
Serious AEs
3.8%
Results posted
Sep 2021
Primary outcome: Primary: Mean Difference of Change in Volume (mL) at 6 Months After Baseline Versus Pre-treatment in the Nasal Dorsum/Nasal Root Between Restylane Perlane Treatment Group and No-treatment Control — 0.82; 0.11 mL

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Restylane Perlane (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Galderma R&D
Primary completion
Dec 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Mean Difference of Change in Volume (mL) at 6 Months After Baseline Versus Pre-treatment in the Nasal Dorsum/Nasal Root Between Restylane Perlane Treatment Group and No-treatment Control
0.82; 0.11

Summary

The purpose of this study is to determine the safety and efficacy of using Restylane Perlane to shape the nasal dorsum and/or nasal root in comparison with a no-treatment control group

Eligibility Criteria

Inclusion Criteria

  • Chinese origin
  • Subject with desire to shape the nasal dorsum and/or nasal root
  • Subjects who, in the opinion of the investigator, can achieve a clinically meaningful aesthetic correction of their nose with ≤ 1 ml Restylane Perlane

Exclusion Criteria

  • Subjects with previous nasal surgery, including grafts or implants to the nose area
  • Subjects requiring filler treatment around the tip of the nose or between the eyebrows (glabella region) to achieve a good aesthetic outcome
  • Subjects with a history of chronic sinusitis or rhinitis
  • Subjects who have previously received aesthetic treatment in the forehead, glabellar and/or nose area with a dermal filler
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02216851). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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