N/A
N=89
Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery.
Patients Waiting for Coronary Artery Bypass Graft Surgery · Patients Waiting for Aortic Valve Repair or Replacement · Patients Waiting for Mitral Valve Repair or Replacement · Patients Waiting for Combined Procedures. (CAGB and Valve)
Bottom Line
View on ClinicalTrials.gov: NCT02219815 ↗Enrolled (actual)
89
Serious AEs
3.7%
Results posted
Oct 2021
Primary outcome: Primary: Proportion of Patients With Hospital Length of Stay Greater Than 7 Days. — 20; 16 Participants
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Prehab Intervention (Behavioral)
- Age
- Adult, Older Adult · 60+ yrs
- Sex
- All
- Sponsor
- St. Boniface Hospital
- Primary completion
- Jun 2018
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Proportion of Patients With Hospital Length of Stay Greater Than 7 Days. |
20; 16 | — |
| SECONDARY Baseline Exercise Capacity |
— | — |
| SECONDARY Preoperative Exercise Capacity |
— | — |
| SECONDARY 3-Month Exercise Capacity |
— | — |
| SECONDARY 1-Year Exercise Capacity |
— | — |
| SECONDARY Baseline Physical Activity Behaviour |
— | — |
| SECONDARY Preoperative Physical Activity Behaviour |
— | — |
| SECONDARY 3-Month Physical Activity Behaviour |
— | — |
| SECONDARY 1-Year Physical Activity Behaviour |
— | — |
| SECONDARY Baseline Health-Related Quality of Life |
— | — |
| SECONDARY Preoperatve Health-Related Quality of Life |
— | — |
| SECONDARY 3-Month Health-Related Quality of Life |
— | — |
| SECONDARY 1-Year Health-Related Quality of Life |
— | — |
| SECONDARY Baseline Frailty |
— | — |
| SECONDARY Preoperative Frailty |
— | — |
| SECONDARY 3-Month Frailty |
— | — |
| SECONDARY 1-Year Frailty |
— | — |
| SECONDARY Baseline Anxiety |
— | — |
| SECONDARY Preoperative Anxiety |
— | — |
| SECONDARY 3-Month Anxiety |
— | — |
| SECONDARY 1-Year Anxiety |
— | — |
| SECONDARY Baseline Depression |
— | — |
| SECONDARY Preoperative Depression |
— | — |
| SECONDARY 3-Month Depression |
— | — |
| SECONDARY 1 Year Depression |
— | — |
| SECONDARY Postoperative Major Adverse Events |
— | — |
| SECONDARY Postoperative Cardiac Rehabilitation Attendance |
— | — |
Summary
The PREHAB study is a clinical trial where frail patients waiting for heart surgery are randomly chosen to either receive the current standard of care or to participate in an 8-week exercise/education program at a community-based cardiac rehabilitation facility. Patients can wait for elective heart surgery for as long as 3-4 months. During this time, individuals are often fearful of making things worse, causing them to stop being active and further deteriorate their physical condition. This wait period presents a potential opportunity for health care providers to engage the patient to take control of their self-managed care prior to surgery with the intent of improving post-surgical outcomes. Patients randomized to the PREHAB intervention group will participate in supervised exercise twice per week in a program designed to improve physical functioning and exercise capacity. The investigators hypothesize that the PREHAB program for frail elderly patients awaiting an elective cardiac surgery will reduce frailty, improve exercise capacity, improve physical activity behaviour, improve in-hospital outcomes, improve clinical outcomes 3 months and 1 year postoperatively, and improve overall quality of life.
Eligibility Criteria
Inclusion Criteria
- Patients aged 60 years and older, undergoing elective isolated coronary artery bypass grafting (CABG), aortic valve repair/replacement for moderate aortic stenosis or severe regurgitation, mitral valve repair/replacement for moderate stenosis or severe regurgitation or combined CABG/valve procedures
- Patients with Clinical Frailty Score (CFS) ≥3 (vulnerable) and 40 mmHg or > 10 mmHg respectively)
- Dynamic left ventricular (LV) outflow obstruction
- Patients who have demonstrated exercise induced ventricular arrhythmias or have experienced a recent hospitalization for arrhythmias
- Patients who have cognitive deficits that would preclude rehabilitation
- Patients who have physical limitations that would preclude rehabilitation
- Patients who are unable to attend the Prehab program
Data sourced from ClinicalTrials.gov (NCT02219815). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.