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N/A N=223 Randomized Double-blind Other

Effect of Iron/Zinc-Biofortified Pearl Millet on Growth and Immunity in Children Aged 12-18 Months in India

Iron Deficiency · Zinc Deficiency

Enrolled (actual)
223
Serious AEs
0.0%
Results posted
Mar 2026
Primary outcome: Primary: Hemoglobin (g/dL) — 10.90; 10.30 g/dL

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
FeZnPM (Other); CtrlPM (Other)
Age
Pediatric · 0+ yrs
Sex
All
Sponsor
Cornell University
Primary completion
Jul 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Hemoglobin (g/dL)
0.10; -0.20
PRIMARY
Hemoglobin (g/dL)
0.10; -0.20
PRIMARY
Iron Status
7.30; 4.70
PRIMARY
Iron Status
7.30; 4.70
PRIMARY
Iron Status BRINDA Adjusted
-1.27; -1.99
PRIMARY
Iron Status BRINDA Adjusted
-1.27; -1.99
PRIMARY
Physical Growth
-0.2; -0.2
PRIMARY
Physical Growth
-0.2; -0.2
PRIMARY
Physical Growth
-0.2; -0.2
PRIMARY
Physical Growth
-0.2; -0.2
PRIMARY
Immune Function
23.08; 0.74
PRIMARY
Immune Function
23.08; 0.74

Summary

In this study, iron- and zinc-biofortified pearl millet will be fed to young children in Mumbai, Maharashtra, India over a period of nine months to measure iron status, growth and immune function in comparison to children receiving non-biofortified pearl millet.

Eligibility Criteria

Inclusion Criteria

  • Age 12 months, 0 days to 18 months, 30 days (at time of screening/baseline visit)
  • Hemoglobin ≥9 g/dL

Exclusion Criteria

  • Age less than 12 months, 0 days or older than 18 months, 30 days (at time of screening/baseline visit)
  • Hemoglobin 1 day hospitalization
  • Children who do not have a caretaker to bring him/her to feeding center
  • Possibility of migrating out of the slum dwelling for longer than 4 weeks
  • Prior or current consumption of iron or zinc supplements in the past 1 year
  • Any known dietary allergies
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02233764). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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