N/A
N=28
Short-term Cardiovascular Benefits of Wearing Particulate-filtering Respirators
Autonomic Nervous System Imbalance · Blood Pressure · Inflammation · Vasoconstriction · Blood Coagulation Disorders
Bottom Line
View on ClinicalTrials.gov: NCT02238028 ↗Enrolled (actual)
28
Serious AEs
0.0%
Results posted
May 2016
Primary outcome: Primary: Heart Rate Variability-LF Power,HF Power,VLF Power — 899.4; 838.5; 519.7; 416.6 ms^2 — p=<0.05
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Wear respirator (Behavioral)
- Age
- Adult · 18+ yrs
- Sex
- All
- Sponsor
- Fudan University
- Primary completion
- Oct 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Heart Rate Variability-LF Power,HF Power,VLF Power |
899.4; 838.5; 519.7; 416.6; 1684.6; 1623.1 | <0.05 sig |
| PRIMARY Blood Pressure |
107.3; 109.0; 70.0; 70.8 | <0.05 sig |
| PRIMARY Heart Rate Variability-SDNN,SDANN, rMSSD |
177.5; 160.7; 49.0 | — |
| PRIMARY Heart Rate Variability-LF/HF |
1.4; 1.5 | — |
| PRIMARY Heart Rate Variability-pNN50 |
24.0; 20.5 | — |
| PRIMARY Circulating Biomarkers--Fibrinogen，vWF |
2.5; 2.5; 24.5; 27.1 | — |
| PRIMARY Circulating Biomarkers--P- Selectin,VCAM-1 |
164.0; 200.3; 1480.3; 1808.0 | — |
| PRIMARY Circulating Biomarkers--ET-1 |
109.9; 121.5 | — |
Summary
An intervention study to assess the short-term cardiovascular effects of reducing personal air pollution exposure by wearing particulate filtering respirators.
Eligibility Criteria
Inclusion Criteria
- Equal to or older than 18 years old,
- No history of smoking and alcohol addiction.
- No chronic diseases, such as hypertension,diabetes,chronic obstructive pulmonary disease or other respiratory/cardiovascular diseases reported by volunteers.
- No respiratory or allergic diseases, like asthma, rhinitis,or other allergic diseases.
Exclusion Criteria
- Current smokers
- Chronic drug use due on cardiovascular or respiratory diseases
Data sourced from ClinicalTrials.gov (NCT02238028). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.