Phase 4
Completed N=37
Optimizing Surgical Conditions During Laparoscopic Herniotomy With Deep Neuromuscular Blockade
Laparoscopic Herniotomy
Source: ClinicalTrials.gov NCT02247466 ↗
Enrolled (actual)
37
Serious AEs
0.0%
Results posted
Jul 2019
Primary outcomePrimary: Improvement of Surgical Workspace — 0; 1; 0; 0 Participants
◆ Published Evidence
Emerging
18citations · ~2 / year
Deep neuromuscular blockade and surgical conditions during laparoscopic ventral hernia repair: A randomised, blinded study.
Summary
The purpose of this study is to investigate surgical work space and surgical conditions in patients scheduled for laparoscopic umbilical, -linea alba and incisional herniotomy. The patients will act as their own control with evaluation of surgical work space and surgical conditions during both deep NMB and no NMB.
Linked Publications (2)
-
Deep neuromuscular blockade and surgical conditions during laparoscopic ventral hernia repair: A randomised, blinded study.
-
Neuromuscular blockade during laparoscopic ventral herniotomy: protocol for a randomised controlled trial.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Improvement of Surgical Workspace |
0; 1; 0; 0; 0; 4 | — |
| SECONDARY Surgical Conditions While Suturing |
0; 0; 0; 0; 0; 2 | — |
| SECONDARY Operating Time |
61; 64 | — |
| SECONDARY Suturing Time |
10; 9 | — |
| SECONDARY Contractions |
1; 0 | — |
| SECONDARY Insufflator Alarms |
0; 0 | — |
| SECONDARY Continuous Abdominal Contractions |
0; 0 | — |
| SECONDARY Recurrences of Hernias |
— | — |
Eligibility Criteria
Inclusion Criteria
- Patients > 18 years old
- Elective laparoscopic umbilical herniotomy, incisional herniotomy and linea alba - herniotomy
- Can read and understand Danish
- Informed consent
Exclusion Criteria
- Known allergy to sugammadex, rocuronium or mivacurium
- Known homozygous variants in the butyrylcholinesterase gene
- Severe renal disease, defined by S-creatinine> 0.200 mmol/L, GFR < 30ml/min or hemodialysis)
- Neuromuscular disease that may interfere with neuromuscular data
- Lactating or pregnant (Women of child bearing potential must take a urine pregnancy test at the day of the operation. The test will be provided by the hospital staff).
- Indication for rapid sequence induction
Data sourced from ClinicalTrials.gov (NCT02247466) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.