N/A N=20 Randomized Single-blind Treatment

Comparison of Autogenous Periosteal Pedicle Graft and Collagen Membrane in Management of Periodontal Intrabony Defects

Chronic Periodontitis

Bottom Line

View on ClinicalTrials.gov: NCT02248103 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Oct 2015

Primary outcome: Primary: Clinical Attachment Level — 6.42; 6.15; 3.52; 3.6 mm

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Periosteal pedicle graft (Procedure); Bioresorbable collagen membrane (Biological)
Age: Adult · 35+ yrs
Sex: All
Sponsor: Cairo University
Primary completion: Apr 2014

Outcome Measures

Outcome	Result	p-value
PRIMARY Clinical Attachment Level	6.42; 6.15; 3.52; 3.6	—
SECONDARY Pocket Depth	6.92; 6.82; 3.17; 3.15	—
SECONDARY Bone Defect Area	8.37; 9.25; 4.42; 5.7	—

Summary

A clinical and radiographic evaluation of autogenous periosteal pedicle graft in comparison with collagen membrane for management of periodontal intrabony defects.

Eligibility Criteria

Inclusion Criteria

Severe chronic periodontitis patients with at least two sites with pocket depth ≥ 6 mm and clinical attachment level ≥ 5 mm, with radiographic evidence of bone loss 2- or 3-wall intrabony defect depth ranging from 3 to 6 mm as detected in periapical radiographs
The facial surface of teeth adjacent to the interproximal defect should be free of extensive recession and marginal bone loss, with at least a 4 to 5 mm band of keratinized gingiva to allow for periosteal manipulation

Exclusion Criteria

Pregnant women
Subjects had <22 permanent teeth
Having any given systemic disease
Taking any type of medication and/or antibiotic therapy during the 3 months before the study
Received periodontal treatment within the past 12 months
Current or former smokers

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Data sourced from ClinicalTrials.gov (NCT02248103). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.