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N/A Completed N=12 Randomized Single-blind Treatment

Investigation of a Novel Sleep Surface for Treatment of Positional Sleep Apnea

Sleep Apnea, Obstructive
Source: ClinicalTrials.gov NCT02250417 ↗
Enrolled (actual)
12
Serious AEs
0.0%
Results posted
Aug 2018
Primary outcomePrimary: Apnea-hypopnea Index (AHI)- Intention to Treat Analysis — 9.8; 12.6 events/hr

Summary

Body position during sleep influences the severity of obstructive sleep apnea (OSA). The AHI is the number of times per hour of sleep that the airway temporarily collapses at the level of the tongue or soft palate. In a significant number of individuals with OSA, the severity of the condition as measured by the apnea-hypopnea index (AHI), increases in the supine (back) position and lowers in the lateral (side) position. This is called positional OSA. The primary objective of this study is to determine whether sleeping with a novel sleep surface (Wave sleep surface) that is used on top of a regular bed reduces the AHI in those with positional OSA.

Outcome Measures

OutcomeResultp-value
PRIMARY
Apnea-hypopnea Index (AHI)- Intention to Treat Analysis
9.8; 12.6
SECONDARY
Objective Sleep Quality
379.8; 363.7; 424.1; 414.3; 38.8; 36.5
SECONDARY
Sleep Efficiency
89.9; 87.9

Eligibility Criteria

Inclusion Criteria

We will recruit subjects who are:

  • 18 years of age and above
  • Willing and able to give informed consent
  • Prior sleep study done based on previous clinical evaluation by the subject's treating physician in the course of usual clinical care and performed no more than 12 months prior to enrollment that meets the following:
  • overall AHI 5-30 events/hr
  • at least 20 minutes of recorded sleep in the supine and nonsupine postures
  • positional OSA defined as > 50% reduction in the AHI between the supine and nonsupine postures and AHI 16 or a prior history of falling asleep while driving
  • Unstable medical problem such as uncontrolled hypertension.
  • Body Mass Index (BMI) > 45 kg/m2
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02250417). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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