Phase 4
Completed N=18
Trial of IV NTG for CD After Second Stage Arrest for the Prevention of Uterine Extension
Prolonged Second Stage of Labor
Source: ClinicalTrials.gov NCT02265965 ↗
Enrolled (actual)
18
Serious AEs
0.0%
Results posted
May 2020
Primary outcomePrimary: Number of Participants With Uterine Extension of Hysterotomy — 3; 4 Participants
◆ Published Evidence
Emerging
7citations · ~1 / year
The association between nitroglycerin use and adverse outcomes in women undergoing cesarean delivery in the second stage of labor.
Summary
Randomized controlled clinical trial of IV nitroglycerin at cesarean delivery for second stage arrest of descent to prevent or uterine extension at the hysterectomy site.
Linked Publications
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The association between nitroglycerin use and adverse outcomes in women undergoing cesarean delivery in the second stage of labor.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants With Uterine Extension of Hysterotomy |
3; 4 | — |
| PRIMARY Umbilical Artery Blood pH |
7.3; 7.3 | — |
| PRIMARY Number of Participants With Deliveries After Which Neonate is Admitted to NICU |
1; 2 | — |
| PRIMARY Number of Participants With Deliveries in Which Cord Blood Base Deficit is More Negative Than or Equal to Negative 12 |
7; 11 | — |
| PRIMARY APGAR at 5 Minutes |
9; 9 | — |
| SECONDARY Fetal Extraction Time in Seconds |
104.9; 131 | — |
| SECONDARY Total Operative Time in Minutes |
68.3; 74.2 | — |
| SECONDARY Surgical Blood Loss |
935.7; 1036.4 | — |
Eligibility Criteria
Inclusion Criteria: women 37weeks or greater gestation diagnosed with second stage arrest of descent undergoing cesarean delivery -
Exclusion Criteria: elective, active phase arrest cesarean delivery, successful operative vaginal delivery
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Data sourced from ClinicalTrials.gov (NCT02265965) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.