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N/A Completed N=29 Randomized Quadruple-blind Treatment

Effect of Intra-Oral Photobiomodulation on Orthodontic Treatment Time

Malocclusion
Source: ClinicalTrials.gov NCT02267850 ↗
Enrolled (actual)
29
Serious AEs
0.0%
Results posted
Mar 2018
Primary outcomePrimary: Overall Orthodontic Treatment Time for OrthoPulse™ and Non-OrthoPulse™ Treated Patients. — 19.0; 21.2 months

Summary

The aim of this study is to determine the effect of OrthoPulse™, an intra-oral LED (Light Emitting Diode) photobiomodulation device, on orthodontic treatment time. This is a double-blinded RCT with half the patients receiving treatment from a sham non-functional device, serving as controls, and the other half receiving light therapy treatment from a functional OrthoPulse™. Orthodontic treatment time for the sham-control patients are compared to that of the OrthoPulse™ patients.

Outcome Measures

OutcomeResultp-value
PRIMARY
Overall Orthodontic Treatment Time for OrthoPulse™ and Non-OrthoPulse™ Treated Patients.
19.0; 21.2

Eligibility Criteria

Inclusion Criteria

  • Presence of permanent dentition
  • Eligible and scheduled for full mouth fixed orthodontic treatment.
  • Class I or Class II malocclusion (no more than ½ cusp in Class II)
  • Non-extraction in all quadrants
  • Non-smoker, non-use of chewing tobacco
  • Good oral hygiene
  • No adjunct treatment such as extra or intraoral appliances
  • Age 12-40

Exclusion Criteria

  • Pregnant females
  • Patient is currently enrolled in another clinical study
  • Non-steroidal Anti-Inflammatory drug (NSAID) use during study (Acetominophen acceptable)
  • Periodontally involved teeth
  • Use of bisphosphonates
  • Unerupted erupted teeth
  • Teeth blocked out of alignment and unable to engage initial arch wire
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02267850). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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