N/A N=22 Randomized Double-blind Treatment

Analgesic Efficacy of Intravenous Ibuprofen in Biliary Colic

Biliary Colic

Bottom Line

View on ClinicalTrials.gov: NCT02268955 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

May 2019

Primary outcome: Primary: Pain Score 120 Minutes After Study Medication Administration — 3.0; 0.3 score on a scale

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: IV Ibuprofen (Drug); Saline (Drug)
Age: Adult · 18+ yrs
Sex: All
Sponsor: Valleywise Health
Primary completion: Jun 2017

Outcome Measures

Outcome	Result	p-value
PRIMARY Pain Score 120 Minutes After Study Medication Administration	3.0; 0.3	—

Summary

The aim of this study is to assess the analgesic efficacy of intravenous ibuprofen given in the Emergency Department for the treatment of biliary colic. We hypothesize that intravenous ibuprofen will provide a clinically significant drop in self-reported patient pain level as measured by the visual analog scale.

Eligibility Criteria

Inclusion Criteria

Patients ages 18-55
Present to ED with right upper quadrant (RUQ) abdominal pain
Suspected diagnosis of biliary colic
Negative pregnancy test for women of childbearing potential (complete POC testing form)
No history of cholecystectomy

Exclusion Criteria

Patient age 55
Incarcerated
Hemodynamic instability
Inability to reliably self-report or communicate pain intensity and pain relief
Taking Warfarin
Cannot consent of are not competent to consent
Hepatic, renal, cardiac failure
NSAID or morphine allergy
History congenital bleeding diathesis or platelet dysfunction
Peptic ulcer diseases
Are otherwise unsuitable for the study in the opinion of the investigator/sub-investigators

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02268955). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.