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N/A Completed N=55 Randomized Quadruple-blind Supportive Care

Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?

Pain Management
Source: ClinicalTrials.gov NCT02276495 ↗
Enrolled (actual)
55
Serious AEs
0.0%
Results posted
Oct 2024
Primary outcomePrimary: Pain Score — 5; 4.5; 4 units on a scale — p=0.668

Summary

The purpose of the study is to determine the effect of a single injection adductor canal block (ACB) on pain scores within 24 hours post total knee arthroplasty (TKA).

Outcome Measures

OutcomeResultp-value
PRIMARY
Pain Score
5; 4.5; 4 0.668
SECONDARY
Opioid Use
38; 0; 26 0.006 sig
SECONDARY
Ambulation Distance
140; 350; 95 0.013 sig

Eligibility Criteria

Inclusion Criteria

  • Males and Females age 18+ years old having total knee arthroplasty (TKA) at UCI Medical Center
  • American Society of Anesthesiologists physical status I to III

Exclusion Criteria

  • Allergy to local anesthetics
  • Pregnancy
  • Nursing Mothers
  • Children <18 years of age
  • Renal impairment (GFR<60 mL/min/1.73m2)
  • Hepatic Impairment (active hepatitis, elevated AST or ALT, jaundice)
  • Opioid tolerant patients (defined as greater than 30 mg Morphine equivalent consumed daily)
  • Patients that are diabetic with peripheral neuropathy
  • BMI greater than 40
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02276495). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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