N/A
N=55
Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty?
Pain Management
Bottom Line
View on ClinicalTrials.gov: NCT02276495 ↗Enrolled (actual)
55
Serious AEs
0.0%
Results posted
Oct 2024
Primary outcome: Primary: Pain Score — 5; 4.5; 4 units on a scale — p=0.668
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- ACB Control - 20 ml saline injection for ACB (Other); ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block (Drug); Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline (Drug)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- University of California, Irvine
- Primary completion
- Jun 2020
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Pain Score |
5; 4.5; 4 | 0.668 |
| SECONDARY Opioid Use |
38; 0; 26 | 0.006 sig |
| SECONDARY Ambulation Distance |
140; 350; 95 | 0.013 sig |
Summary
The purpose of the study is to determine the effect of a single injection adductor canal block (ACB) on pain scores within 24 hours post total knee arthroplasty (TKA).
Eligibility Criteria
Inclusion Criteria
- Males and Females age 18+ years old having total knee arthroplasty (TKA) at UCI Medical Center
- American Society of Anesthesiologists physical status I to III
Exclusion Criteria
- Allergy to local anesthetics
- Pregnancy
- Nursing Mothers
- Children <18 years of age
- Renal impairment (GFR<60 mL/min/1.73m2)
- Hepatic Impairment (active hepatitis, elevated AST or ALT, jaundice)
- Opioid tolerant patients (defined as greater than 30 mg Morphine equivalent consumed daily)
- Patients that are diabetic with peripheral neuropathy
- BMI greater than 40
Data sourced from ClinicalTrials.gov (NCT02276495). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.