N/A
Completed N=69
A Pilot Study to Assess the Amnesic Properties of Propofol in Pediatric Patients
Pediatric Pateints · Amnesic Properties of Propofol
Source: ClinicalTrials.gov NCT02278003 ↗
Enrolled (actual)
69
Serious AEs
0.0%
Results posted
Jan 2018
Primary outcomePrimary: Sedation Threshold — 29; NA; 1; 0 Participants
Summary
The goal of this study is to extend findings of propofol's effects on memory, as measured in volunteer research studies, to a clinical setting.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Sedation Threshold |
29; NA; 1; 0 | — |
| SECONDARY Memory Threshold |
0.71; 0.93 | — |
Eligibility Criteria
Inclusion Criteria
- The patient must be between 4 and 14 yrs of age and be undergoing a therapeutic or diagnostic procedure with or without sedation
- The patient must be able to comprehend and perform the task (naming pictures)
- The patient must have a minimum weight of 8 kg
Exclusion Criteria
- Allergy to propofol (for those patients requiring sedation)
- Procedure of short duration (< 15 min)
- Pregnancy
- Recent use (within 5 half-lives) of centrally acting medications that could affect concentration (e.g. diphenhydramine)
Data sourced from ClinicalTrials.gov (NCT02278003). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.