Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
N/A N=13 Diagnostic

PET/MRI and PET/CT in Diagnosing Younger Patients With Cancer

Childhood Cancer

Bottom Line

View on ClinicalTrials.gov: NCT02287636 ↗
Enrolled (actual)
13
Serious AEs
0.0%
Results posted
Feb 2020
Primary outcome: Primary: Diagnostic Accuracy of PET/MRI

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
fludeoxyglucose F 18 (Radiation); positron emission tomography (Procedure); computed tomography (Procedure); magnetic resonance imaging (Procedure)
Age
Pediatric
Sex
All
Sponsor
Case Comprehensive Cancer Center
Primary completion
Apr 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Diagnostic Accuracy of PET/MRI		 — —
PRIMARY
Diagnostic Accuracy of PET/CT		 — —
SECONDARY
SUVs Using PET/MRI		 — —
SECONDARY
SUVs Using PET/CT		 — —
SECONDARY
Radiation Dose Reduction Associated With PET/MRI		 — —
SECONDARY
Time Effort Associated With the PET/MRI		 — —

Summary

This pilot clinical trial studies how well positron emission tomography (PET)/magnetic resonance imaging (MRI) works compared to PET/computed tomography (CT) in diagnosing younger patients with cancer. PET/MRI and PET/CT are procedures that combine the pictures from a PET scan and an MRI scan or a CT scan. The PET and MRI scans or PET and CT scans are done at the same time with the same machine. The combined scans give more detailed pictures of areas inside the body than either scan gives by itself. It is not yet known whether PET/MRI works better than PET/CT in diagnosing younger patients with cancer.

Eligibility Criteria

Inclusion Criteria

  • Patients who are referred by their physician for clinically indicated diagnostic fludeoxyglucose F 18 (18F-FDG) PET/CT (with or without clinically indicated diagnostic MRI)
  • Subjects with malignancies including hematologic disorders
  • Subjects NOT requiring sedation or anesthesia
  • Stable physical medical conditions (patients conscious and comfortable, scheduled for an elective diagnostic imaging)

Exclusion Criteria

  • Subjects who are unable or unwilling to give their assent to both examinations if > 7 years old
  • Subjects requiring general anesthesia or sedation in order to undergo PET/CT or MRI
  • Subjects unable to undergo magnetic resonance (MR) scanning due to exclusion by University Hospitals-Case Medical Center restriction policies for Magnetic Resonance Imaging (UHCMC MRI restriction policies) as mentioned in the standard UHCMC MRI informed consent form
  • Previously known allergies against MRI contrast agents (exclusion criterion only for contrast enhanced MRI)
  • Pregnant or breast feeding subjects, as determined by standard questionnaire administered prior to scanning
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02287636). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

Back to search