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N/A N=52 Randomized Treatment

Randomized, Controlled Study to Compare Straumann® VivOss™ to Geistlich Bio-Oss® in Sinus Floor Augmentation.

Healthy

Enrolled (actual)
52
Serious AEs
1.9%
Results posted
Aug 2019
Primary outcome: Primary: Ratio of Newly Formed Bone to Residual Bone Graft in Patients Treated With Straumann® VivOss™ Compared to Geistlich Bio-Oss® — 1.37; 0.69 ratio — p=0.001

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Straumann VivOss (Device); Geistlich Bio-Oss (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Institut Straumann AG
Primary completion
Oct 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Ratio of Newly Formed Bone to Residual Bone Graft in Patients Treated With Straumann® VivOss™ Compared to Geistlich Bio-Oss®
1.37; 0.69 0.001 sig
SECONDARY
Survival Rate of Study Implants (Based on Subjects)
24; 22
SECONDARY
Success Rate of Study Implants
25; 25

Summary

A randomized controlled clinical trial to investigate the capability of Straumann® VivOss™ compared to Geistlich Bio-Oss in sinus floor augmentation to demonstrate superiority of Straumann® VivOss™ compared to Geistlich Bio-Oss in regards to the ratio of newly formed bone to residual bone substitute.

Eligibility Criteria

Inclusion Criteria

  • Subject must have voluntarily signed the informed consent before any study related action
  • Males and females with at least 18 years of age (including 18 years)
  • Subject needs augmentation procedure in the sinus to prepare for implant placement.
  • Subject must have a residual bone height of 2 to 4 mm.
  • Adequate oral hygiene ((Full mouth plaque index (O'Leary, et al. 1972 ) 10 cigarettes per day or tobacco equivalents or chew tobacco
  • Conditions or circumstances, in the opinion of the investigator, which would prevent completion of study participation or interfere with analysis of study results, such as history of non-compliance or unreliability
  • Physical or mental disabilities that would interfere with the ability to perform adequate oral hygiene
  • Current pregnancy (pregnancy test) and breastfeeding women

Secondary exclusion criterium:

Defects of the Schneider Membrane

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02288182). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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