N/A
N=91
Pharmacy Home Adherence Reporting and Monitoring Outcomes Study
Diabetes · Hypertension · Hypercholesterolemia
Bottom Line
View on ClinicalTrials.gov: NCT02306122 ↗Enrolled (actual)
91
Serious AEs
0.0%
Results posted
Jan 2022
Primary outcome: Primary: Probability of Resolution of Nonadherence Within 30 Days — .4286; .4290; .4554; .4437 Proportion of resolved NAEs within 30 — p=<0.01
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Pharmacist calls patient unless physician cancels call (Behavioral); Patient nonadherence information sent to physician (Behavioral); Pharmacist calls patient if physician requests call (Behavioral); Doctor receives information and may be allowed certain actions (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Brown University
- Primary completion
- Feb 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Probability of Resolution of Nonadherence Within 30 Days |
.4286; .4290; .4554; .4437 | <0.01 sig |
| PRIMARY Duration of Nonadherence Event |
40.91; 39.46; 41.35; 41.04 | <0.01 sig |
| SECONDARY Probability of Physician Viewing Nonadherence Event Information |
0.2822; 0.3856; 0.3257 | <0.01 sig |
| SECONDARY Probability of Pharmacist Action Triggered |
0.6102; 0.1903 | <0.01 sig |
Summary
This study is a pilot test of an intervention that delivers timely diagnostic information about medication nonadherence to doctors, and then offers the services of clinical pharmacists to treat these nonadherence problems. Participating doctors will be notified when a patient is 10 days late refilling a medication for diabetes, hypertension, or hypercholesterolemia. In one randomization arm the pharmacist will contact the patient as the default option (with no action required by the doctor), and in the other the pharmacist will contact the patient only if the doctor actively chooses that the pharmacist take action. Patients of participating doctors will be randomized to 1) one of these two pharmacist options, 2) an information only control arm in which the doctor gets adherence information but does not have access to a pharmacist for that patient, and 3) a no information control arm. The investigators' central hypothesis is that the pharmacist will be consulted more often when intervention by the pharmacist is the default outcome and that the default pharmacist intervention will be the most beneficial for adherence outcomes.
Eligibility Criteria
Physician Inclusion Criteria:
- New England Quality Care Alliance (NEQCA) primary care physicians of adult patients insured through large commercial insurer partner
Patient Inclusion Criteria:
- Adult patients of consented New England Quality Care Alliance (NEQCA) primary care physicians
- Insured through large commercial insurer partner
- Prescribed chronic medications for one or more of the three study conditions in the past six months
Patient Exclusion Criterion:
- On the insurer's "do not contact" list
Data sourced from ClinicalTrials.gov (NCT02306122). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.