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N/A N=250 Screening

Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis Compared to Mammography

Breast Cancer · Tumors, Breast · Cancer Screening

Enrolled (actual)
250
Serious AEs
0.0%
Results posted
Jan 2019
Primary outcome: Primary: Number of Participants With Imaging Data Collected — 249; 1 Participants

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
FFDM (Device); DBT (Device)
Age
Adult, Older Adult · 30+ yrs
Sex
Female
Sponsor
GE Healthcare
Primary completion
Jul 2017

Outcome Measures

OutcomeResultp-value
PRIMARY
Number of Participants With Imaging Data Collected
249; 1

Summary

The aim of this recruitment plan (ADAPT-SCR) is to collect image and other data on both digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) from asymptomatic women undergoing screening mammography.

Eligibility Criteria

Inclusion Criteria

  • Women aged 30 years or older (≥30 years old);
  • Asymptomatic women scheduled for screening mammography or have completed a screening mammogram within the past 30 days;
  • Mammography completed on a General Electric (GE) GE FFDM system (with craniocaudal (CC) and mediolateral oblique (MLO) views) at the site or another clinical facility;
  • Are able and willing to comply with study procedures;
  • Have signed and dated the informed consent form;
  • Are either surgically sterile or postmenopausal or, if of childbearing potential, the possibility of pregnancy is remote based on a documented negative patient history and, optionally, a negative urine pregnancy test (if subject requests one).

Exclusion Criteria

  • Have been previously included in this study;
  • Have a history of breast cancer and are in active treatment. However, subjects with a prior lumpectomy (> 5 years prior) who receive only routine screening mammography views can be included;
  • Have breasts too large to be adequately positioned on 24 x 31 centimeter (cm) FFDM digital receptor without anatomical cut off during either FFDM or DBT examination;
  • Have participated in (within the prior 30 days) another trial of an investigational product expected to interfere with study procedures or outcomes;
  • Have breast implant(s);
  • Have reconstructed breast(s).
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02306265). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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