N/A
Completed N=150
Preoxygenation With Positive Inspiratory Pressure During Induction of Anesthesia
Anesthesia
Source: ClinicalTrials.gov NCT02313766 ↗
Enrolled (actual)
150
Serious AEs
0.0%
Results posted
Jan 2015
Primary outcomePrimary: Time for Preoxygenationfrom Face Mask Positioning to FEO2=90% — 190; 153; 140 seconds
Summary
Adults patients scheduled for elective surgery were randomly allocated to receive preoxygenation with spontaneous breathing, positive pressure ventilation (positive inspiratory pressure: 12 cmH2O) without PEEP, and with PEEP (positive inspiratory pressure: 12 cmH2O, PEEP: 6 cmH2O). Preoxygenation time was measured from face mask positioning to FEO2=90% (FEO2 : expired fraction of O2). After endotracheal tube placement the time until SpO2=93% (SpO2 : peripheral oxygen saturation) was measured during monitored apnoea. Patient's discomfort was recorded (visual analogue scale).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Time for Preoxygenationfrom Face Mask Positioning to FEO2=90% |
190; 153; 140 | — |
| SECONDARY Time Until SpO2=93% |
305; 370; 345 | — |
| SECONDARY Discomfort of the Preoxygenation Phase Self Reported by the Patient |
0; 8; 0 | — |
Eligibility Criteria
Inclusion Criteria
- American Society of Anesthesiologists (ASA) physical status I and II
- Scheduled surgery with general anaesthesia and oro-tracheal intubation
Exclusion Criteria
- rapid sequence induction
- anticipated difficult mask ventilation
- anticipated difficult intubation
- refusal to participate to the study and to sign informed consent
Data sourced from ClinicalTrials.gov (NCT02313766). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.