N/A N=90 Randomized Double-blind Treatment

Low Dose Peri- Operative Intra Venous Teranexamic Acid Reduces Blood Loss After Total Knee Arthroplasty: A Double Blind Randomized Placebo Controlled Clinical Trial

Knee Arthroplasty, Total

Bottom Line

View on ClinicalTrials.gov: NCT02327117 ↗

Enrolled (actual)

Serious AEs

0.0%

Results posted

Jul 2016

Primary outcome: Primary: Hb Level 48 Hours After Total Knee Arthroplasty — 10.92; 10.23 gr/dL

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Tranexamic Acid (Drug); Normal saline (Drug)
Age: Pediatric, Adult, Older Adult
Sex: All
Sponsor: Isfahan University of Medical Sciences
Primary completion: Jan 2015

Outcome Measures

Outcome	Result	p-value
PRIMARY Hb Level 48 Hours After Total Knee Arthroplasty	10.92; 10.23	—

Summary

Total Knee Arthroplasty (TKA) is a common orthopedic surgery usually leads to Bleeding. The null hypothesis of this study was that TA has no effect on post surgical bleeding in patients undergoes TKA.

Eligibility Criteria

Inclusion Criteria

Individuals with osteoarthritis who indicated for primary TKA.

Exclusion Criteria

Previous history of ceberovascular diseases
Previous history of myocardial infarction
Candidates for bilateral TKA

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Data sourced from ClinicalTrials.gov (NCT02327117). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.