N/A
N=20
Timing of Caloric Intake, Diet-induced Thermogenesis and Hormonal Pattern
Diet-induced Thermogenesis
Bottom Line
View on ClinicalTrials.gov: NCT02343380 ↗Enrolled (actual)
20
Serious AEs
0.0%
Results posted
Dec 2015
Primary outcome: Primary: Intra-individual Variation in Morning Diet-induced Thermogenesis (DIT) Evaluated by Calorimetric Exam After the Consumption of a Meal at 8:00 am Compared With Evening DIT Evaluated by Calorimetric Exam After the Consumption of the Same Meal at 8:00 pm — 327.5; 237.0 kcal/min
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- calorimetric exam after a standard meal (Other)
- Age
- Adult · 20+ yrs
- Sex
- All
- Sponsor
- University of Turin, Italy
- Primary completion
- Jul 2014
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Intra-individual Variation in Morning Diet-induced Thermogenesis (DIT) Evaluated by Calorimetric Exam After the Consumption of a Meal at 8:00 am Compared With Evening DIT Evaluated by Calorimetric Exam After the Consumption of the Same Meal at 8:00 pm |
327.5; 237.0 | — |
| SECONDARY Variation in Morning Glucose and Insulin Area-Under the Curve (AUC)s After the Consumption of a Meal at 8:00 am Compared With Evening Glucose and Insulin AUCs After the Consumption of the Same Meal at 8:00 pm |
15383; 17183; 6969; 8598 | — |
| SECONDARY Variation in Morning Triglyceride and Free Fatty Acid (FFA) Area-Under the Curve (AUC)s After the Consumption of a Meal at 8:00 am Compared With Evening Glucose and Insulin AUCs After the Consumption of the Same Meal at 8:00 pm |
11721; 12363; 38.7; 54.7 | — |
| SECONDARY Intra-individual Variations in the Values of Adrenalin and Noradrenalin, After the Morning and Evening Meal Consumption |
4543.5; 3020.7; 37504.9; 32718.4 | — |
| SECONDARY Intra-individual Variations in the Values of Acylated Ghrelin After the Morning and Evening Meal Consumption |
8013.5; 9631.3 | — |
| SECONDARY Intra-individual Variations in the Values of Glucagon-like Peptide-1 After the Morning and Evening Meal Consumption |
— | — |
Summary
The investigators aim at analyzing whether eating a standard meal in the evening (at 8:00 pm) determines in the same individuals a lower diet-induced thermogenesis (DIT) and a different hormonal response than the consumption of the same meal in the morning (at 8:00 am).
The primary outcome is: the intra-individual variation in DIT after the evening and morning meal consumption.
The secondary outcomes are the intra-individual variations in glucose, triglyceride, insulin, free fatty acids, leptin, glucagon-like peptide-1, acylated ghrelin, adrenalin, noradrenalin, after the evening and morning meal consumption.
Eligibility Criteria
Inclusion Criteria
- body mass index 19-26 kg/m2
- habitual moderate exercise level
Exclusion Criteria
- any acute or chronic diseases
- menopause
- any drugs or supplementations
- any alimentary restrictions or specific diets
- being a shift or night workers
- unable to give a written informed consent
Data sourced from ClinicalTrials.gov (NCT02343380). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.