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N/A N=138

Surgical Stress Markers for Postoperative Complications: a Prospective Study

Operative Procedures, Complications

Enrolled (actual)
138
Serious AEs
0.7%
Results posted
May 2020
Primary outcome: Primary: Predictive Value of Postoperative Albumin Decrease in Terms of Surgical Stress and Postoperative Complications — 11.3 g/L

Study Design & Population

Study type
Observational
Phase
N/A
Interventions
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Lausanne Hospitals
Primary completion
Dec 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Predictive Value of Postoperative Albumin Decrease in Terms of Surgical Stress and Postoperative Complications
11.3

Summary

The aim of this study is to evaluate the predictive value of albumine, C-reactive protein (CRP), procalcitonin, and lactates in terms of surgical stress and postoperative complications. These biomarkers will be measured from the day before surgery until postoperative day four in patients undergoing major surgery. Major surgery was defined as esophagus, gastric, liver, pancreas, endocrine, retroperitoneal, or colorectal procedures including an organ resection for benign or malignant disease and lasting more than 2 hours.

Eligibility Criteria

Inclusion Criteria

  • Patients over 18 years old
  • Patients undergoing esophagus, gastric, liver, pancreas, endocrine, retroperitoneal, or colorectal surgery
  • Operation time more than 2 hours
  • Operation including an organ resection for benign or malignant disease

Exclusion Criteria

  • Immunosuppressive therapy
  • Cognitive impairment or language comprehension problems
  • Absence of the consent form prior to first blood sample
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02356484). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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