N/A
N=15
Prone Breath Hold Technique to Decrease Cardiac and Pulmonary Doses in Women Receiving Left Breast Radiotherapy
Breast Cancer
Bottom Line
View on ClinicalTrials.gov: NCT02379988 ↗Enrolled (actual)
15
Serious AEs
0.0%
Results posted
May 2023
Primary outcome: Primary: The Radiation Dose in Gy to the Heart and Lung Using Two Radiation Techniques. — 0.9317; 0.7186; 0.6523; 0.8746 Gy — p==0.0063
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Verify radiation dose to heart and lung (Radiation)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- Female
- Sponsor
- University of Arizona
- Primary completion
- Jul 2016
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY The Radiation Dose in Gy to the Heart and Lung Using Two Radiation Techniques. |
0.9317; 0.7186; 0.6523; 0.8746; 2.6159; 2.6231 | =0.0063 sig |
| SECONDARY Determination of Cardiac Dose and Lung Dose Reduction in Women Receiving Prone Breast Radiotherapy When Inspiratory Gating is Added. |
15.7029; 7.1869; 17.9426; 26.6156 | =0.0010 sig |
| SECONDARY Heart Mean Dose Based on Breast Volume |
109.4; 77.5; 71.6; 64.3 | =0.01 sig |
| SECONDARY Determination of Left Anterior Artery (LAD) Dose Reduction in Women Receiving Prone Breast Radiotherapy When Inspiratory Gating is Added. |
9.9154; 8.3896 | =0.7776 |
Summary
This is a pilot study to determine whether the addition of inspiratory hold (breath holding) can decrease the radiation dose that the heart and lung receive for patients being treated for left sided breast cancer.
Eligibility Criteria
Inclusion Criteria
- Patients of Dr. Gonzalez
- ≥18 years of age
- Node-negative left breast cancer
- Invasive or DCIS breast cancer
- Prior lumpectomy
- Deemed appropriate for treatment in the prone position by the treating physician
- Able to tolerate prone position and breath hold during CT simulation
Exclusion Criteria
- <18 years of age
- Patients requiring treatment in supine position
Data sourced from ClinicalTrials.gov (NCT02379988). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.