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N/A N=115 Randomized Single-blind Treatment

Cognitive Rehab and Exposure Treatment for Hoarding

Hoarding Disorder

Enrolled (actual)
115
Serious AEs
0.0%
Results posted
Sep 2024
Primary outcome: Primary: Saving Inventory Revised — 59.9; 55.3; 25.2; 23.0 score on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Cognitive Rehabilitation and Exposure/Sorting Treatment (CREST) (Behavioral); Exposure Therapy (ET) (Behavioral)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
VA Office of Research and Development
Primary completion
Dec 2021

Outcome Measures

OutcomeResultp-value
PRIMARY
Saving Inventory Revised
59.9; 55.3; 25.2; 23.0; 16.6; 14.4
SECONDARY
UCSD Performance-Based Skills Assessment (UPSA)
49.0; 49.1; 18.3; 18.0; 16.2; 15.3
SECONDARY
UCSD SORT Test
33.1; 31.2; 32.5; 32.7; 34.2; 34.2
SECONDARY
Specific Levels of Functioning Test (SLOF)
123.9; 128.0; 25.6; 24.7; 26.6; 26.7

Summary

This project will utilize a novel behavioral intervention for hoarding disorder that takes into account age and neurocognitive factors. The goal of this project is to gain knowledge on how treatment components may or may not work for Veterans with hoarding disorder. Further, the investigators hope to increase understanding of functional and long term outcomes in response to hoarding treatment.

Eligibility Criteria

Inclusion Criteria

  • Veterans age 18-85
  • Hoarding Disorder diagnosis outlined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)6 as measured by the Structured Interview for Hoarding Disorder (SIHD)67
  • HD as a primary diagnosis
  • Stable on medications for at least 12 weeks, with no pharmacologic changes expected or made during the 12-month study
  • Voluntary consent to participate

Exclusion Criteria

  • Diagnosis of:
  • psychotic disorder
  • substance abuse disorder as measured by the Mini-International Neuropsychiatric Interview (M.I.N.I.)68
  • Current or history of any neurodegenerative disease
  • Active suicidal ideation
  • Concurrent participation in psychotherapy or ET for HD, or prior history of CREST for HD
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02402647). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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