Phase 4
Completed N=100
Same-Day Mifepristone-Misoprostol Compared to Misoprostol Only for Surgical Abortion Cervical Preparation
Induced Abortion
Source: ClinicalTrials.gov NCT02412618 ↗
Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Mar 2022
Primary outcomePrimary: Initial Cervical Dilation — 11.7; 10.9 mm
◆ Published Evidence
Emerging
18citations · ~2 / year
A randomized controlled trial evaluating same-day mifepristone and misoprostol compared to misoprostol alone for cervical preparation prior to second-trimester surgical abortion.
Summary
A randomized double---blinded comparison of same---day mifepristone and misoprostol with misoprostol only for cervical preparation in second---trimester surgical abortion in 100 women at 14 0/7---19 6/7 weeks gestation.
Linked Publications
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A randomized controlled trial evaluating same-day mifepristone and misoprostol compared to misoprostol alone for cervical preparation prior to second-trimester surgical abortion.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Initial Cervical Dilation |
11.7; 10.9 | — |
| SECONDARY Patient Acceptability and Assessment of Pain and Side Effects (5-point Likert Scale) |
4; 4; 4; 4 | — |
Eligibility Criteria
Inclusion Criteria
- healthy women
- eligible for non---urgent D&E
- 14 0/7 weeks to 19 6/7 weeks gestation, confirmed by sonogram
Exclusion Criteria
- emergent need for D&E
- fetal demise
- intolerance
- allergy or contraindication to mifepristone or misoprostol
Data sourced from ClinicalTrials.gov (NCT02412618) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.