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N/A N=86 Prevention

Cleancision IntRaoperative Contamination prEvention Study

Wound Contamination · Colorectal Surgery

Enrolled (actual)
86
Serious AEs
19.8%
Results posted
Jul 2017
Primary outcome: Primary: Efficacy (Enteric Bacterial Contamination on the Exposed Surface of the CleanCision Sheath Compared to the Protected Incision Edge) — 33.3; 9.5 % of participants with contamination — p=<0.001

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
CleanCision (Device)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Prescient Surgical
Primary completion
Jul 2016

Outcome Measures

OutcomeResultp-value
PRIMARY
Efficacy (Enteric Bacterial Contamination on the Exposed Surface of the CleanCision Sheath Compared to the Protected Incision Edge)
33.3; 9.5 <0.001 sig
PRIMARY
Safety (Serious Adverse Events Directly Attributable to the Device)
SECONDARY
Efficacy (Bacterial Contamination on the Exposed Surface of the CleanCision Sheath Compared to the Protected Incision Edge)
34.5; 11.9 <0.001 sig

Summary

This study entitled, An Evaluation of the Safety and Efficacy of the CleanCision Wound Retraction and Protection System in Protecting Surgical Incisions from Intraoperative Contamination When Used during Colorectal Surgery, is designed to evaluate contamination at the wound incision site when the CleanCision is used during surgery.

Eligibility Criteria

Inclusion Criteria

  • Age 18 and older
  • BMI 15-45, inclusive
  • Colorectal surgery patient, planned resection
  • Incision length meets labeling requirements
  • Written informed consent using the governing IRB approved form

Exclusion Criteria

  • Patients with a pre-existing stoma
  • Patients undergoing emergent colorectal surgery
  • Known history of contact hypersensitivity or allergy to device materials
  • Prior laparotomy or abdominal surgery within a timeframe that may present a safety risk or compromise study results
  • Active infection, sepsis or systemic antibiotic therapy within timeframe that may impact safety or study results
  • Active participation in any other clinical study of an experimental drug or device that may impact safety or study results
  • Postsurgical life expectancy is less than the study follow up period
  • Subject is pregnant or lactating
  • Subject is under incarceration
  • Subject considered to be inoperable following exploratory surgery
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02413879). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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