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N/A N=25 Randomized Double-blind Treatment

Dispensing Study for the Phenacite Project

Ametropia

Enrolled (actual)
25
Serious AEs
0.0%
Results posted
Nov 2020
Primary outcome: Primary: Subjective Ratings of Lens Comfort — 86.50; 90.13 units on a scale

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Phenacite (Device); comfilcon A (Device)
Age
Adult · 18+ yrs
Sex
All
Sponsor
CooperVision, Inc.
Primary completion
Jul 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
Subjective Ratings of Lens Comfort
66.46; 71.71
PRIMARY
Subjective Ratings of Lens Comfort
66.46; 71.71
PRIMARY
Over Refraction for Optimized Distance Acuity
-0.10; 0.00; -0.02; 0.00
PRIMARY
Binocular Distance Visual Acuity - High Illumination High Contrast
-0.19; -0.20
PRIMARY
Binocular Distance Visual Acuity - High Illumination High Contrast
-0.19; -0.20
PRIMARY
Binocular Distance Visual Acuity - Low Illumination High Contrast
0.00; 0.00
PRIMARY
Binocular Distance Visual Acuity - Low Illumination High Contrast
0.00; 0.00
PRIMARY
Binocular Near Visual Acuity - High Illumination High Contrast
-0.20; -0.18
PRIMARY
Binocular Near Visual Acuity - High Illumination High Contrast
-0.20; -0.18
PRIMARY
Binocular Near Visual Acuity - Low Illumination High Contrast
-0.02; -0.03
PRIMARY
Binocular Near Visual Acuity - Low Illumination High Contrast
-0.02; -0.03
SECONDARY
Lens Fit - Post Blink Movement
0.24; 0.23; 0.25; 0.24
SECONDARY
Lens Fit - Post Blink Movement
0.24; 0.23; 0.25; 0.24
SECONDARY
Push - Up Test for Lens Tightness
52.83; 49.35; 51.30; 48.70
SECONDARY
Push - Up Test for Lens Tightness
52.83; 49.35; 51.30; 48.70
SECONDARY
Lens Mobility Rating
2.91; 3.08; 3.00; 3.10
SECONDARY
Lens Mobility Rating
2.91; 3.08; 3.00; 3.10
SECONDARY
Overall Lens Fit Acceptance
3.25; 3.34; 3.32; 3.36
SECONDARY
Overall Lens Fit Acceptance
3.25; 3.34; 3.32; 3.36
SECONDARY
Subjective Ratings for Vision Quality - Distance Vision
85.33; 88.88
SECONDARY
Subjective Ratings for Vision Quality - Distance Vision
85.33; 88.88
SECONDARY
Subjective Ratings for Vision Quality - Near Vision
84.83; 85.88
SECONDARY
Subjective Ratings for Vision Quality - Near Vision
84.83; 85.88
SECONDARY
Subjective Ratings for Vision Quality - Computer Vision
85.04; 89.08
SECONDARY
Subjective Ratings for Vision Quality - Computer Vision
85.04; 89.08
SECONDARY
Subjective Ratings for Vision Quality - Overall Vision
85.96; 88.63
SECONDARY
Subjective Ratings for Vision Quality - Overall Vision
85.96; 88.63
SECONDARY
Corneal Staining Extent
0.02; 0.00; 0.00; 0.00; 0.00; 0.00
SECONDARY
Conjunctival Staining
0.48; 0.38; 0.11; 0.18; 0.00; 0.05

Summary

Dispensing Study for the Phenacite Project. The investigational test lens was not the final optical design and the study was not used for design validation.

Eligibility Criteria

Inclusion Criteria

  • Oculo-visual examination in the last two years
  • Between 18 and 35 years of age and has full legal capacity to volunteer
  • Has read and understood the informed consent letter
  • Is willing and able to follow instructions and maintain the appointment schedule
  • Is correctable to a visual acuity of 20/25 or better (in each eye) with their habitual correction or 20/20 best corrected
  • Currently wears, or has previously successfully worn, soft contact lenses between -1.00D and -4.00D
  • Spherical Contact Lens Rx between -1.00 and -4.00 and spectacle cylinder ≤-0.75
  • Has not worn lenses for at least 12 hours before the initial visit
  • Has a subjective response at baseline, which indicates suitability for this study
  • Currently spends a minimum of 4 hours a day; 5 days a week on digital devices and can replicate this time during the study period
  • Is willing and able to wear the study contact lenses a minimum of 10 hours per day; 5 days a week.

Exclusion Criteria

  • Has never worn contact lenses before
  • Any systemic disease affecting ocular health
  • Is using any systemic or topical medications that will affect ocular health
  • Has known sensitivity to the diagnostic pharmaceuticals or study products used in this study.
  • Has any ocular pathology or anomaly that would affect the wearing of the lenses
  • Has persistent, clinically significant corneal or conjunctival staining using sodium fluorescein dye
  • Is aphakic
  • Has anisometropia of >1.00
  • Has undergone corneal refractive surgery
  • Has strabismus
  • Has any ocular amblyopia >= 1line of HC Visual Acuity
  • Is participating in any other type of eye related clinical or research study
  • Has participated in study CV-14-32.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02436005). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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