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N/A N=100 Randomized Triple-blind Treatment

Comparative Study of Ropivacaine and Ropivacaine With Dexmeditomedine in TAP Blocks

Pregnancy

Enrolled (actual)
100
Serious AEs
0.0%
Results posted
Jul 2016
Primary outcome: Primary: The Time After the TAP Block When Rescue Analgesia Was First Sought — 13.12; 18.21 Hours

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Ropivacaine + Dexmedetomidine (Drug); Ropivacaine (Other)
Age
Adult · 18+ yrs
Sex
Female
Sponsor
Tata Main Hospital
Primary completion
Nov 2015

Outcome Measures

OutcomeResultp-value
PRIMARY
The Time After the TAP Block When Rescue Analgesia Was First Sought
13.12; 18.21
SECONDARY
Total Dose of Required Morphine in 24 Hours Postoperatively
8.16; 6.21
SECONDARY
Adverse Effects Like Pruritus, Nausea and Vomiting
1; 0; 2; 1; 47; 49

Summary

Comparative study of Ropivacaine and Ropivacaine with dexmedetomidine in transversus abdominis plane (TAP) block for post-operative analgesia in patients undergoing Caesarean Section.

Eligibility Criteria

Inclusion Criteria

  • ASA 1 or 2
  • Age above 18 years
  • Patients for Lower Section Cesarean Section surgery

Exclusion Criteria

  • Patient refusal
  • Allergy to study medications
  • Localized infection over injection point
  • Patients with significant coagulopathies and with contraindications to regional anesthesia
  • Patients with a history of cardiac, respiratory, renal or hepatic failure
  • Psychological disorders
  • Chronic use of pain medications or adrenoreceptors agonists or antagonists.
  • BMI >35 or weight < 50 kilograms
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02472522). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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