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Phase 3 N=5,451 Randomized Double-blind Prevention

Strategies to Reduce Injuries and Develop Confidence in Elders

Accidental Falls · Wounds and Injuries

Enrolled (actual)
5,451
Serious AEs
41.2%
Results posted
Mar 2021
Primary outcome: Primary: First Adjudicated Serious Fall-Related Injury — 4.87; 5.34 events per 100 person years of follow-up — p=0.245

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
Evidence-based tailored fall prevention (Other); Usual care (Other)
Age
Older Adult · 70+ yrs
Sex
All
Sponsor
Brigham and Women's Hospital
Primary completion
Dec 2019

Outcome Measures

OutcomeResultp-value
PRIMARY
First Adjudicated Serious Fall-Related Injury
4.87; 5.34 0.245
SECONDARY
First Self-reported Fall-related Injury
25.64; 28.62 0.004 sig
SECONDARY
Time to Self-reported Falls
SECONDARY
Physical Function
58.45; 57.73 0.309
SECONDARY
Disability
55.16; 54.57 0.528
SECONDARY
Anxiety
11.63; 12.53 0.037 sig
SECONDARY
Depression
11.75; 12.94 0.009 sig
SECONDARY
Fear of Falling
16.03; 16.10 0.897

Summary

The aim of this pragmatic cluster-randomized trial is to determine the effectiveness of an evidence-based, patient-centered multifactorial fall injury prevention strategy in community dwelling older adults at risk of falls recruited from 86 primary care practices around the U.S.

Eligibility Criteria

Inclusion Criteria

  • The patient is at least 70 years of age.
  • The patient must answer 'yes' to one or more of the following questions:
  • Have you fallen and hurt yourself in the past year?
  • Have you fallen 2 or more times in the past year?
  • Are you afraid that you might fall because of balance or walking problems?

Exclusion Criteria

  • The patient is enrolled in hospice.
  • The patient resides in a nursing home.
  • The patient is not capable of providing informed consent (or assent), and a proxy is not available.
  • The patient does not speak English or Spanish
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02475850). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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