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Phase 3 Completed N=5,451 Randomized Double-blind Prevention

Strategies to Reduce Injuries and Develop Confidence in Elders

Accidental Falls · Wounds and Injuries
Source: ClinicalTrials.gov NCT02475850 ↗
Enrolled (actual)
5,451
Serious AEs
41.2%
Results posted
Mar 2021
Primary outcomePrimary: First Adjudicated Serious Fall-Related Injury — 4.87; 5.34 events per 100 person years of follow-up — p=0.245
◆ Published Evidence
Established ▲ Trending
24citations · ~5 / year
Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well-Being: The STRIDE Study.
Journal of the American Geriatrics Society · 2021 · Open access · Likely link

Summary

The aim of this pragmatic cluster-randomized trial is to determine the effectiveness of an evidence-based, patient-centered multifactorial fall injury prevention strategy in community dwelling older adults at risk of falls recruited from 86 primary care practices around the U.S.

Linked Publications (5)

  • Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well-Being: The STRIDE Study.
    Journal of the American Geriatrics Society · 2021 · 24 citations · Open access · Likely link
  • Effect of the STRIDE fall injury prevention intervention on falls, fall injuries, and health-related quality of life.
    Journal of the American Geriatrics Society · 2022 · 17 citations · Open access · Likely link
  • Costs of fall injuries in the STRIDE study: an economic evaluation of healthcare system heterogeneity and heterogeneity of treatment effect.
    Cost effectiveness and resource allocation : C/E · 2023 · 4 citations · Open access · Likely link
  • Assessing readiness to use electronic health record data for outcome ascertainment in clinical trials - A case study.
    Contemporary clinical trials · 2024 · 2 citations · Open access · Likely link
  • A case study of ascertainment bias for the primary outcome in the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) trial.
    Clinical trials (London, England) · 2021 · 2 citations · Open access · Likely link

Outcome Measures

OutcomeResultp-value
PRIMARY
First Adjudicated Serious Fall-Related Injury
4.87; 5.34 0.245
SECONDARY
First Self-reported Fall-related Injury
25.64; 28.62 0.004 sig
SECONDARY
Time to Self-reported Falls
SECONDARY
Physical Function
58.45; 57.73 0.309
SECONDARY
Disability
55.16; 54.57 0.528
SECONDARY
Anxiety
11.63; 12.53 0.037 sig
SECONDARY
Depression
11.75; 12.94 0.009 sig
SECONDARY
Fear of Falling
16.03; 16.10 0.897

Eligibility Criteria

Inclusion Criteria

  • The patient is at least 70 years of age.
  • The patient must answer 'yes' to one or more of the following questions:
  • Have you fallen and hurt yourself in the past year?
  • Have you fallen 2 or more times in the past year?
  • Are you afraid that you might fall because of balance or walking problems?

Exclusion Criteria

  • The patient is enrolled in hospice.
  • The patient resides in a nursing home.
  • The patient is not capable of providing informed consent (or assent), and a proxy is not available.
  • The patient does not speak English or Spanish
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02475850) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.

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