N/A
Completed N=50
Effect of Tetanus on Neuromuscular Junction Monitor Performance in Pediatric Patients
Muscle Relaxation
Source: ClinicalTrials.gov NCT02498678 ↗
Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Dec 2015
Primary outcomePrimary: Train of Four 0,9 (90%) — 49.9; 41.7 minutes
Summary
The objective of this study is to assess the performance of acceleromyography as a method of evaluation of muscle relaxation after application of tetanus stimulation to obtain stability of responses before administration of neuromuscular blocking agents.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Train of Four 0,9 (90%) |
49.9; 41.7 | — |
| PRIMARY T1 Height |
95.3; 69.3 | — |
| SECONDARY Time to Obtain T1 Height Stability |
195; 116 | — |
| SECONDARY Monitor Settings - Electric Current |
48.2; 47.2 | — |
| SECONDARY Monitor Settings - Sensitivity |
128; 103.8 | — |
Eligibility Criteria
Inclusion Criteria
- Physical Status 1-2, aged 2 to 11 years, regardless of genders) who will undergo abdominal and / or perineal surgery, with planned surgical time greater than 60 minutes
Exclusion Criteria
- Patients with diseases or medications that are known to interfere with neuromuscular transmission, hepatic or renal dysfunction or allergy to medications used in the study will be excluded
Data sourced from ClinicalTrials.gov (NCT02498678). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.