N/A
N=50
Effect of Tetanus on Neuromuscular Junction Monitor Performance in Pediatric Patients
Muscle Relaxation
Bottom Line
View on ClinicalTrials.gov: NCT02498678 ↗Enrolled (actual)
50
Serious AEs
0.0%
Results posted
Dec 2015
Primary outcome: Primary: Train of Four 0,9 (90%) — 49.9; 41.7 minutes
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Tetanus (Procedure)
- Age
- Pediatric · 2+ yrs
- Sex
- All
- Sponsor
- University of Sao Paulo General Hospital
- Primary completion
- Jul 2015
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Train of Four 0,9 (90%) |
49.9; 41.7 | — |
| PRIMARY T1 Height |
95.3; 69.3 | — |
| SECONDARY Time to Obtain T1 Height Stability |
195; 116 | — |
| SECONDARY Monitor Settings - Electric Current |
48.2; 47.2 | — |
| SECONDARY Monitor Settings - Sensitivity |
128; 103.8 | — |
Summary
The objective of this study is to assess the performance of acceleromyography as a method of evaluation of muscle relaxation after application of tetanus stimulation to obtain stability of responses before administration of neuromuscular blocking agents.
Eligibility Criteria
Inclusion Criteria
- Physical Status 1-2, aged 2 to 11 years, regardless of genders) who will undergo abdominal and / or perineal surgery, with planned surgical time greater than 60 minutes
Exclusion Criteria
- Patients with diseases or medications that are known to interfere with neuromuscular transmission, hepatic or renal dysfunction or allergy to medications used in the study will be excluded
Data sourced from ClinicalTrials.gov (NCT02498678). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.