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N/A N=80 Randomized Triple-blind Prevention

Skin Prep to Reduce Postoperative Shoulder Infection

Shoulder Infection

Enrolled (actual)
80
Serious AEs
0.0%
Results posted
Jan 2020
Primary outcome: Primary: Skin Swab and Culture With Colony Forming Units (CFUs) — 39; 51; 35; 22 negative skin cultures — p=0.68

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Skin Prep Chlorhexidine (Drug); Skin Prep Benzoyl Peroxide (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Maryland, Baltimore
Primary completion
Jul 2018

Outcome Measures

OutcomeResultp-value
PRIMARY
Skin Swab and Culture With Colony Forming Units (CFUs)
39; 51; 35; 22 0.68
SECONDARY
Surgical Site Infection That Requires Antibiotics
0; 0

Summary

Propionibacterium acnes is the most common pathogen identified from a surgical site infection in the shoulder. Standard skin preps do not prevent this type of infection. Patients will undergo either a chlorhexidine or benzoyl peroxide prep in days leading up to surgery. Bacterial burden will be determined at the time of surgery.

Eligibility Criteria

Inclusion Criteria

  • Age >18
  • Indicated for shoulder surgery

Exclusion Criteria

  • History of previous shoulder infection
  • Allergy to Chlorhexidine or benzoyl peroxide
  • Current use of anti-acne medicine around the shoulder
  • Patient is pregnant or concerned about pregnancy
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT02510144). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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