N/A
N=145
Trauma Informed Guilt Reduction Therapy
Guilt · Shame · Post-traumatic Stress Disorders
Bottom Line
View on ClinicalTrials.gov: NCT02512445 ↗Enrolled (actual)
145
Serious AEs
0.0%
Results posted
May 2025
Primary outcome: Primary: Trauma Related Guilt Inventory - Guilt Severity — 2.5; 2.5; 1.6; 2.2 score on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Trauma Informed Guilt Reduction Therapy (Behavioral); Supportive Care Therapy (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- Veterans Medical Research Foundation
- Primary completion
- Jun 2023
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Trauma Related Guilt Inventory - Guilt Severity |
2.5; 2.5; 1.6; 2.2 | — |
| SECONDARY Change in Clinician Administered Posttraumatic Stress Disorder (PTSD) Scale - 5 (CAPS-5) |
38.2; 38.6; 23.3; 30.9 | — |
| SECONDARY Change in Patient Health Questionnaire - 9 (PHQ-9) |
15.1; 14.4; 9.8; 12.5 | — |
| SECONDARY Change in Internalized Shame Scale |
51.4; 49.6; 37.4; 41.9 | — |
| SECONDARY Change in World Health Organization Quality of Life - Brief |
43.7; 44.5; 48.3; 44.4 | — |
| SECONDARY Change in Brief Symptom Inventory-18 |
53.1; 54.0; 47.3; 49.0 | — |
Summary
The goal of this project is to determine if a 6-session psychotherapy intervention will help Veterans feel less deployment-related guilt and less distress related to their guilt. Half of the participants will receive the guilt focused intervention and half will receive a supportive intervention. A supplemental pilot study added in FY2021 will examine the intervention for pandemic-related guilt events.
Eligibility Criteria
Inclusion Criteria
- Participant Served in OEF/OIF/OND, has post-traumatic guilt related to deployment event (for pandemic supplement in 2021, has guilt related to pandemic event)
Exclusion Criteria
- Moderate or severe cognitive impairment, acute suicidality, current severe substance use disorder, unmanaged psychosis or mania
Data sourced from ClinicalTrials.gov (NCT02512445). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.